Miriplatin-loaded liposome,as a novel mitophagy inducer,suppresses pancreatic cancer proliferation through blocking POLG and TFAM-mediated mtDNA replication

导出学术成果认领

作者 Xiaowei Wang ^[1] Mengyan Wang ^[2] Meilian Cai ^[2] Rongguang Shao ^[2] Guimin Xia ^[3] Wuli Zhao ^[2] 学术成果认领

作者单位 State Key Laboratory of Respiratory Health and Multimorbidity,Key Laboratory of Antibiotic Bioengineering,Ministry of Health,Laboratory of Oncology,Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China;Pharmaceutics Department,Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China ^[1] State Key Laboratory of Respiratory Health and Multimorbidity,Key Laboratory of Antibiotic Bioengineering,Ministry of Health,Laboratory of Oncology,Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China ^[2] Pharmaceutics Department,Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China ^[3]

关键词 Miriplatin-loaded liposome Pancreatic cancer Caveolae-mediated endocytosis Caveolin-1 Mitophagy Mitochondria DNA POLG TFAM

栏目名称 Original articles

DOI 10.1016/j.apsb.2023.07.009

发布时间 2023-12-08

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药学学报（英文版）

2023年13卷11期

4477-4501页

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Miriplatin-loaded liposome,as a novel mitophagy inducer,suppresses pancreatic cancer proliferation through blocking POLG and TFAM-mediated mtDNA replication

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Miriplatin-loaded liposome,as a novel mitophagy inducer,suppresses pancreatic cancer proliferation through blocking POLG and TFAM-mediated mtDNA replication

药学学报（英文版）

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药学学报（英文版）

相关期刊

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