换一批
换一批摘要篇首： 1 IntroductionPsychotic major depression (PMD),which responds poorly to tricyclic anti-depressants, is a distinct syndrome of depression. hy percortisolemia (cortisone hypersecretion), a biological abnormality existing in many patients with PMD, has led to various theoretical and empirical rationales for the potential therapeutic use of anti-glucocorticoid agents in the treatment of depression.
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关键词
重型精神病性抑郁症肾上腺皮质醇增多症下丘脑-垂体-肾上腺轴糖皮质激素受体拮抗剂psychotic major depressionhypercortisolemiahypothalamic-pituitary-adrenal axisglucocorticoid receptorantagonist
主题词
受体, 糖皮质激素(Receptors, Glucocorticoid)精神病(Psychotic Disorders)性(Sex)抑郁症(Depressive Disorder)肾上腺皮质(Adrenal Cortex)
栏目名称
综述与述评
DOI
10.3321/j.issn:0513-4870.2005.11.001
发布时间
2005-12-01
基金项目
科技部资助项目
中国科学院资助项目
上海市科技发展基金
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