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Randomized controlled trial comparing open anterograde anatomic radical retropubic prostatectomy with retrograde technique

摘要Objective:Radical prostatectomy is the recommended treatment for localized prostate cancer;however,it is an invasive procedure that can leave serious morbidity.Robot-assisted radical prostatectomy was introduced with the aim of reducing postoperative morbidity and facilitating rapid recovery compared to the traditional Walsh's open radical ret-ropubic prostatectomy.Therefore,a protocol was developed to perform an open prostatec-tomy comparable to that performed by robotics,but without involving novel instrumentation.Methods:A total of 220 patients diagnosed with localized prostate cancer underwent radical prostatectomy.They were divided into two groups:anterograde technique(115 patients)and the retrograde method(105 patients).The study outcomes were observed 3 months after surgery.Results:No differences were found in terms of surgical time,hospital stay,and suction drainage.However,reduced bleeding was observed in the anterograde technique(p=0.0003),with rapid anastomosis duration(p=0.005).Among the patients,60.9% undergo-ing the anterograde technique were continent 3 months after surgery compared to 42.9% treated by the retrograde method(p=0.007).Additionally,fewer complications in terms of the number(p=0.007)and severity(p=0.0006)were observed in the anterograde technique.Conclusion:The anterograde method displayed increased efficiency in reducing complications,compared to the retrograde technique.

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作者 Fabricio B.Carrerette [1] Daniela B.Rodeiro [1] Rui T.F.Filho [1] Paulo A.Santos [1] Celso C.Lara [1] Ronaldo Dami?o [1] 学术成果认领
作者单位 Department of Surgery(Urology),Pedro Ernesto University Hospital of State University of Rio de Janeiro,Rio de Janeiro,Brazil [1]
DOI 10.1016/j.ajur.2021.11.008
发布时间 2024-03-11(万方平台首次上网日期,不代表论文的发表时间)
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