换一批摘要Hepatitis B virus(HBV)establishes chronic infection through strategic manipulation of host metabolic networks,driving a spectrum of hepatic pathologies ranging from hepatitis to cirrhosis and hepato-cellular carcinoma.Mechanistically,HBV reprograms core metabolic pathways,including glycolysis,tricarboxylic acid(TCA)cycle,oxidative phosphorylation,and lipid homeostasis,to fuel its replica-tion machinery and evade immune surveillance.This review systematically synthesizes current evi-dence on HBV-induced glucose/lipid metabolic rewiring,with particular emphasis on how viral-host crosstalk at the metabolic interface sustains viral pathogenesis.
更多相关知识
关键词
Hepatitis B virus(HBV)Metabolic rewiringGlycolysisTCA cycleOxidative phosphorylationLipid metabolism
栏目名称
DOI
10.1016/j.virs.2025.09.008
发布时间
2026-03-31（万方平台首次上网日期，不代表论文的发表时间）
- 浏览0
- 被引0
- 下载0
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
