摘要Bone tissue engineering graft has been widely used in clinic for bone defect.However,the increase of the success rate is still difficult.Bone marrow is rich in bone progenitor cells,cytokines and growth factors,and it is an important natural repository of bioactive components that promoting osteogenesis.Traditional bone marrow enrichment technology can hardly achieve the ideal cell concentration around the scaffold,while selective cell retention technology(SCR)can maximize the enrichment of bone marrow cells that are beneficial to osteogenesis on the graft and improve the survival rate of the graft.In this paper,the basic concepts of bone tissue engineering,the principle of selective cell retention technology and the latest research progress are reviewed.