摘要Although spinal fusion is a basic and routine technique in spinal surgery,there are still great challenges to achieve stable bone graft fusion in elderly patients with spinal degeneration.New technologies and concepts are needed for break through.3D printing technology enables morphological matching for spine surgical implant design and processing.Furthermore,clinical and scientific practitioners have promoted the development of biological matching orthopedic implants,including tissue matching(microstructural modification and improvement),biomechanical matching(SDS theory),and degradation matching(bioactive materials),while the three directions are mutually inclusive and progressive.Biological matching spine implant development in China started relatively late,however,we are still making breakthroughs in many key technical points and approaching the top level in clinical translation.These achievements may help improve the prognosis of spinal fusion in aging spine.Meanwhile,there is still a gap between the current achievements and the widespread application of biological matching spine surgical implants.Further works are required in the future.