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液基薄层细胞学检测对宫颈病变的诊断价值

Diagnostic value of thinPrep liquid-base cytologic test(TCT)examination in patients with cervical disease

摘要目的 探讨液基薄层细胞学检测(TCT)技术对宫颈癌前病变的诊断价值.方法 收集宫颈病变患者1 000例,分别应用TCT(500例)检查及传统巴氏涂片(500例)检查.结果 TCT法满意490例(98.0%),高于传统涂片法的440例(88.0%)(χ~2=3.987,P<0.05);传统涂片法检查ⅡB~V级阳性50例(10.0%)低于TCT法的85例(17.1%)(χ~2=3.923,P<0.05);TCT检查与病理活检的阳性符合率64.7%,明显高于传统涂片法的44.0%(χ~2=3.893,P<0.05).结论 TCT技术明显提高了标本的满意率及宫颈异常细胞检出率,并且与组织病理活检有较高的阳性符合率,适合于临床推广应用.

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abstractsObjective To evaluate the clinical significance of liquid-based cytological test(TCT)examina-tion for screening of cervical disease.Method 1000 case were divided into two groups,500 cases were examined by liquid-based cytological examination.and 500 cases were examined by traditional Papanicoloaou smear.Results TCT satisfied with 490 cases(98.0%)which was higher than the traditional smear method 440 cases(88.0%)(χ~2=3.987,P<0.05);The traditional smear examination ⅡB~V-class positive 50 cases(10.0%)were lower than TGT 85 cases(17.1%)(χ~2=3.923,P<0.05);TCT examination、with biopsy of the positive coincidence rate of 64.7% were significantly higher than the traditional smear 44.0%(χ~2=3.893,P<0.05).Conclusion TCT technology significantly improves satisfaction rates and detection rate of abnormal cells,also with the pathology biopsy have a higher positive coincidence rate,suitable for clinical application.

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DOI 10.3760/cma.j.issn.1008-6706.2010.07.012
发布时间 2010-06-02(万方平台首次上网日期,不代表论文的发表时间)
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