摘要目的：了解2012年全国抗菌药物临床应用专项整治活动开展前后腹股沟疝无张力修补术围手术期抗菌药物应用情况，为规范抗菌药物合理使用及加强规范化管理提供依据。方法分别对某医院2011-2013年每年7～9月份出院的腹股沟疝无张力修补术患者围手术期抗菌药物应用情况进行回顾性调查，对抗菌药物的给药时机、使用率、种类及用药时间进行调查和分析。结果三年的总预防用药率分别为93.24％、47．76％和27．59％，有指征用药率分别为9．19％、65．67％和85．08％，切口甲级愈合率分别为94.59％、98．51％和96．55％。品种选择合理率分别为70．60％、96．88％和91．67％，用药时机合理率分别为71.01％、81．25％和70．83％，总预防用药疗程合理率为33．33％、56．25％和58．33％。结论腹股沟疝无张力修补术原则上不预防使用抗菌药物具有可操作性。深入开展2012年抗菌药物临床应用专项整治活动后，腹股沟疝无张力修补术预防用药水平有了很大的提高，但仍须加强管理抗菌药物预防用药时机选择和总的预防用药疗程。

abstractsObjective To investigate the use of antibacterial drugs in tension -free inguinal hernia repair before and after the 2012 National clinical use of antibiotics special management ,providing the basis for the rational use of antimicrobial drugs and standardized management .Methods Retrospectively investigate the antimicrobial ap-plication in patients undergoing tension-free inguinal hernia repair and discharged from July to September in 2011-2013,and analyzed the timing of administration ,usage,type and treatment time of antimicrobial drugs .Results There were respectively 93.24%,47.76%and 27.59%of patients in the three groups administrated prophylaxis antibacte-rial drugs,and respectively 9.19%,65.67%and 85.08%of patients with indications .The first wound healing rates were respectively 94.59%,98.51% and 96.55%.The rates of reasonable choice of medicines 70.60%,96.88%and 91.67%,respectively;the rates of reasonable timing for medication were 71.01%,81.25%and 70.83%,respec-tively;the rates of reasonable courses of prophylaxis therapy were 33.33%,56.25% and 58.33% respectively. Conclusion The principle of no preventive antibiotics use in tension-free inguinal hernia repair is operable .After en-actment of special management of antibacterial drugs ,the level of preventive medication for tension-free inguinal herni-a repair is improved greatly .However ,it still needs to strengthen the management of antimicrobial prophylaxis timing and overall prophylaxis treatment course .