摘要目的：通过分析围产期孕妇生殖道B族链球菌（GBS ）的感染与不良妊娠结局，为临床医师制定有效地预防和治疗措施提供依据。方法2013年1月至2015年2月，对795例围产期孕妇生殖道分泌物进行 GBS 培养鉴定，观察临床症状及不良妊娠结局，并进行统计学分析。结果795例孕妇中共检出 GBS 携带者256例，带菌率为32．2％。＜30岁组（28．9％）与≥30岁组（42．3％）的带菌率差异有统计学意义（χ2＝19．095，P ＜0．01）。GBS 阳性者与 GBS 阴性者的临床症状发生率（18．8％，8．0％）差异有统计学意义（χ2＝39．514，P ＜0．01）。GBS 阳性组与 GBS 阴性组比较，胎膜早破、早产、宫内感染及新生儿感染发生率的差异均有统计学意义（χ2＝29．355、10．543、31．797、13．291，均 P ＜0．01）。结论围产期孕妇 GBS 带菌率较高，且高龄者易于感染；围产期孕妇感染 GBS 可增加不良妊娠结局的发生，应予以临床干预。

abstractsObjective To analyze the perinatal pregnant women vaginal group B streptococcus (GBS)infec-tion and and adverse pregnancy outcomes and provide evidences which were for clinicians to formulate effective pre-vention and treatment measures.Methods From January 2013 to February 2015,the vaginal secretions were sampled from 795 cases of perinatal pregnant women for culture identification of GBS,and the clinical symptoms and adverse pregnancy outcomes were observed.The final results were statistical analyzed.Results In the 795 pregnant women, there were 256 GBS carriers,the carrier rate was 32.2%.There was statistically significance (χ2 =19.095,P <0.01)between less than 30 years old group (28.9%)and greater than or equal to 30 years old group (42.3%).The different incidence rate of clinical symptoms between GBS negative cases and GBS positive cases (18.8%,8.0%) was also had statistically significance(χ2 =39.514,P <0.01).Compared with the GBS negative groups,the different incidence rate of premature rupture of membranes,preterm delivery,intrauterine infection and neonatal infections of GBS also existed statistical significance (χ2 =29.355,10.543,31.797,13.291,all P <0.01 ).Conclusion The carrier rate of perinatal pregnant women GBS was higher in this region,and the elderly were easier to be infected.Peri-natal pregnant women infected with GBS can increase the occurrence of adverse pregnancy outcomes,and should be given clinical intervention.