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沙美特罗替卡松粉吸入剂与氨茶碱治疗女性缓解期慢性阻塞性肺疾病疗效比较

Comparative efficacy of Salmeterol assigned powder inhaler and Aminophylline Tablets treating female COPD with remission

摘要目的:比较沙美特罗替卡松粉吸入剂与氨茶碱片治疗女性缓解期慢性阻塞性肺疾病(COPD)的效果。方法选择缓解期 COPD 女性患者114例,以数字表法随机分为观察组和对照组各57例。观察组吸入沙美特罗替卡松粉剂,对照组口服氨茶碱片进行治疗。比较两组治疗效果以及 IC、FEV1、FVC、FEV1%等肺功能指标的变化。结果观察组治疗效果达到显著者47.37%(27/57),显著高于对照组的26.32%(15/57)(χ2=4.150,P =0.042),观察组总有效率也更高;观察组治疗后 IC、FEV1、FVC、FEV1%等指标升高明显,TDI、6MWD 也更高,差异有统计学意义(t =5.077、4.746,P =0.000、0.000)。结论沙美特罗替卡松粉吸入剂与氨茶碱片治疗女性缓解期 COPD 均呈现高效结果,但相对来说沙美特罗替卡松粉吸入剂治疗效果更佳,对呼吸困难缓解程度更好。

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abstractsObjective To explore the comparison of efficacy of Salmeterol assigned powder inhaler and Aminophylline Tablets treating female COPD with remission.Methods Selected in remission of COPD in female patients of 114 cases.With digital method were divided into observation group and control group with 57 cases in each group.The observation group inhaled salmeterol and fluticasone propionate powder,while the control group oral amin-ophylline tablets for treatment.Effect and Lung function index,such as IC,FEV1 ,FVC,FEV1 % etc.were compared between the two groups after the treatment.Results The observation group treatment effects achieved significantly accounted for 47.37% (27 /57),which was significantly higher than 26.32% (15 /57)in control group,and the total effective rate of the observation group was higher(χ2 =4.150,P =0.042).In addition,the IC,FEV1 ,FVC,FEV1 %index increased significantly in the observation group after treatment,and the TDI,6MWD was also higher.The difference was statistically significant (t =5.077,4.746,P =0.000,0.000).Conclusion Salmeterol and fluticasone propionate inhalation and aminophylline tablets in the treatment of female remission of COPD showed a high efficient results,but the relative effect of salmeterol and fluticasone propionate inhalation therapy effect is better,the degree of dyspnea alleviated better.

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