摘要目的分析2011-2016年安徽省淮南地区无偿献血者梅毒感染资料,了解献血人群的梅毒感染特征,为今后献血者的招募及保留提供依据和建议.方法采用ELISA法分别对无偿献血标本同时进行梅毒抗体检测,整理梅毒感染相关资料分析梅毒阳性者人群特征及变化趋势.结果2011-2016年共对139 078份无偿献血标本进行梅毒抗体检测,确认阳性847份,阳性率为0.61%.2011-2016年梅毒阳性率呈下降趋势;梅毒阳性者中性别以女性为主,男女比例为1∶1.2;年龄以45~55岁最高(0.79%),最低的是18~24岁(0.25%);梅毒阳性率随文化程度增高而逐渐降低,其中小学及以下最高为1.36%,本科及以上最低为0.29%;重复献血和单位组织的献血者是最为理想的献血人群,梅毒感染率远低于其他献血人群.结论淮南地区无偿献血人群梅毒感染率呈下降趋势,但梅毒对血液安全仍然存在威胁,今后工作中要加强对无偿献血低危人群的宣传招募,要对不同人群有针对性的开展无偿献血宣传.

abstractsObjective To analyze the epidemic characterization of syphilis infection among non-remunerated blood donors based on data of Huainan area from 2011 to 2016,and thus to provide scientific evidence for recruitment and reserve of blood donors in the future.Methods All serum samples were tested for syphilis by screening with ELISA to make definite diagnosis for the samples with positive results.Data of syphilis infection were collected and analyzed for epidemic characterization and trend.Results There were 139 078 serum samples of blood donors,the samples were tested for syphilis and confirmed 847 samples with positive result,the positive rate of syphilis infection was 0.61%.The positive rate of syphilis infection showed a downward trend from 2011 to 2016.Females were more than males and the sex ratio was 1:1.2 among all positive samples.The positive rate of people with 45-55 years old was the highest,and the lowest positive rate came from people with 18-24 years old.The positive rate of syphilis infection increased with the decrease of levels of education,among them,the primary school and below was the highest 1.36%,bachelor degree or above was the minimum 0.29%.Repeated and units-organized blood donors were the most ideal blood donors,and the infection rate of syphilis was much lower than the other donors.Conclusion The positive rate of syphilis infection among non-remunerated blood donors in Huainan area showed a downward trend.Syphilis still remains high threat to the safety of blood.We should strengthen the work of recruitment for the low-risk blood donors,and provide targeted health education propaganda for different blood donors.