摘要目的 探讨不同消毒剂对内镜消毒效果及耐用性的比较.方法 选择2016年1月至2016年9月浙江省武义县第一人民医院内镜中心使用后的内镜428例,采用随机数字表法分为对照组及观察组,每组214例,对照组采用戊二醛处理消毒;观察组采用邻苯二甲醛处理消毒.采样部位为内镜的活检道内腔面,采用无菌注射器抽取10 mL含有中和剂的缓冲液,注入待检内镜活检口,再用15 mL无菌试管从活检出口收集,于2h内送检检测.评价消毒合格率,检测两组消毒剂消毒内镜的内镜腔及表面菌落数,两组消毒剂消毒内镜的耐用性比较.结果 对照组消毒合格率为89.25％,观察组消毒合格率为97.20％,两组内镜消毒合格率差异具有统计学意义(x2=10.69,P=0.001);观察组内镜腔及内镜表面菌落数均低于对照组,差异具有统计学意义(t=3.17,P=0.00;t=26.76,P=0.00);观察组每周期消毒数、平均每天消毒数均高于对照组,差异均具有统计学意义,(t =94.44,P=0.00;t =23.94,P=0.00).结论 采用邻苯二甲醛对内镜进行消毒其消毒效果更好,耐用性更佳,适合内镜室推广应用.

abstractsObjective To explore the effect of different disinfectants on endoscopic disinfection and durability.Methods A total of 428 endoscopes were selected from the endoscopic center of our hospital from January 2016 to September 2016,and they were randomly divided into control group and observation group,each group in 214cases.The control group was treated with glutaraldehyde.The observation group used o-phthalaldehyde treatment disinfection.The sampling site was the endoscopic biopsy cavity surface,sterile syringe was used to extract 10ml containing neutralizer buffer,into the endoscopic biopsy to be tested,and then 15mL sterile test tube from the biopsy outlet collection,was checked within 2h.The sterilization pass rate was evaluated,the disinfectant disinfection endoscopic cavity and the number of surface colonies,disinfectant endoscopic durability in the two groups were compared.Results The disinfection rate was 89.25％ in the control group and 97.20％ in the observation group,the difference of the qualified rate of endoscopic disinfection between the two groups was statistically significant (x2 =10.69,P =0.001).The endoscopic cavity and the number of surface colonies of the observation group were lower than those of the control group (t =3.17,P =0.00;t =26.76,P =0.00).The numbers of disinfection per cycle and per day in the observation group were higher than those in the control group,the differences were statistically significant (t =94.44,P =0.00;t =23.94,P =0.00).Conclusion The use of o-phthalaldehyde for endoscopic disinfection is better,more durable,suitable for endoscopic room to promote the use.