定量影像技术在胰腺癌诊断中的应用
Application of quantitative imaging technique in the diagnosis of pancreatic cancer
摘要胰腺癌是胰腺实质的恶性肿瘤,临床表现不具有特征性,早期检出率低,容易发生转移,且胰腺癌的5年生存率低,预后差.影像技术在临床中应用广泛,随着技术的成熟,影像技术的应用不仅仅局限于图像的显示,目前一些定量影像技术已经成为研究的热点,包括磁共振动态对比增强(DCE-MRI)、体素内不相干运动(IVIM)、CT灌注成像,可以对病灶血流灌注情况及微血管的渗透性进行定量分析,提高对疾病诊断的敏感性,同时可以定量评估药物及放化疗疗效.
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abstractsPancreatic cancer is a malignant tumor,and the clinical manifestations are not characteristic,so it is difficult to diagnose at an early stage, and it has a poor prognosis. Image technology has been widely used in clinical,with mature technology,and the application of image technology not only confined to the image display,but also has become a hot spot of research, including dynamic contrast enhancement magnetic resonance imaging (DCE-MRI),intravoxel incoherent motion ( IVIM),CT perfusion imaging,which could analyze quantitatively the permeability and microvascular of lesions,to improve the sensitivity of diagnosis,and to assess quantitatively the effect of drugs,radiation and chemotherapy.
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