摘要肺炎支原体是儿童呼吸道感染的常见病原体之一,由其感染导致的肺炎支原体肺炎( MPP)多数临床表现轻微、预后较好.但近年来重症或难治病例明显增多,这些病例虽经大环内酯类药物正规治疗后,仍持续发热,影像学表现进行性加重,并极易合并胸腔积液、肺不张、闭塞性支气管炎甚至发生肺坏死等并发症,严重影响了患儿身体健康.因此,寻找能够导致难治性肺炎支原体肺炎( RMPP)发生的相关影响因素,早期识别RMPP,给予早期干预、规范治疗,减少并发症的发生至关重要.在临床中发现MPP临床表现、实验室检查结果、影像学表现等指标均与RMPP发生相关.故本文对上述相关影响因素的研究进展予以综述.

abstractsMycoplasma pneumoniae(MP) is one of the most common pathogens of respiratory tract infections in children.The majority of clinical manifestations of Mycoplasma pneumoniae pneumonia ( MPP) caused by MP infection are mild,and the prognosis is better.However,in recent years,there has been a significant increase in cases of severe or refractory.Although these cases were regularly treated with macrolide drugs,they continued to have fever, and their radiographic appearance were progressively worsened, and pleural effusion, atelectasis, obliterative bronchiolitis are easily combined,and even complications such as lung necrosis,which seriously affected the health of children.Therefore,looking for relevant influencing factors that can lead to the development of refractory Mycoplasma pneumoniae pneumonia ( RMPP), early identification of RMPP, giving early intervention, standard treatment, and reducing the occurrence of complications are of utmost importance.The clinical manifestations,laboratory test results, imaging appearance and other indicators of MPP were found to correlate with the occurrence of RMPP.Therefore,this article reviews the research progress of the above related factors.