摘要目的:分析磁共振T 2 mapping成像技术对青少年颈椎间盘早期退变的诊断价值。 方法:收集2019年11月至2020年9月在温州市中医院行颈椎MRI检查和T 2 mapping扫描检查受检者的临床资料，按照每天低头时间（≥ 2 h）分为观察组和对照组，每组50例。比较两组受检者各节段颈椎间盘髓核对应的T 2值之间的差别；按照Pfirrmann标准对颈椎间盘进行分级，比较不同级别之间T 2值的差别，采用受试者工作特征曲线（ROC曲线）评估T 2值在青少年颈椎间盘早期退变中的诊断效能，计算对应的特异度、灵敏度和曲线下面积（AUC）。 结果:观察组各节段颈椎间盘测得的T 2值均高于对照组，差异均有统计学意义（C2-3、C3-4、C4-5、C5-6、C6-7项目组间 t值依次为5.06、4.47、3.57、2.93、4.98，均 P < 0.05）；观察组受检者，PfirrmannⅡ级例数最多，占42%（21/50）；不同Pfirrmann分级下受检者颈椎间盘髓核T 2值，差异有统计学意义（与PfirrmannⅠ级比较， t=2.62， P=0.018；与PfirrmannⅡ级比较， t=2.12， P=0.045；与PfirrmannⅢ级比较， t=2.24， P=0.049。）；Pfirrmann分级越高，受检者颈椎间盘髓核T 2值最低；ROC曲线显示T 2值在诊断椎间盘早期退变的灵敏度、特异度以及AUC分别为81.2%、79.8%和0.756。 结论:T 2 mapping成像技术可通过定量分析颈椎间盘髓核T 2值，实现对青少年颈椎间盘早期退变的预估，具有较高的诊断价值，该成果具有一定创新性和科学性。

abstractsObjective:To analyze the value of magnetic resonance T 2 mapping in the diagnosis of early cervical disc degeneration in adolescents. Methods Patients who underwent cervical MRI examination and magnetic resonance T 2 mapping in Wenzhou Hospital of Traditional Chinese Medicine between November 2019 and September 2020 were included in this study. They were divided into observation and control groups ( n = 50 per group) according to the time of lowering their heads (≥ 2 hours) every day. The T 2 values corresponding to the nucleus pulposus of cervical intervertebral disc in each segment was compared between the two groups. Cervical disk degeneration was graded using the Pfirrmann classification. T 2 value was compared between different Pfirrmann disc grades. The efficacy of T 2 value in the diagnosis of early cervical disc degeneration in adolescents was evaluated using the receiver operating characteristic curve. The specificity and sensitivity of T 2 value in the diagnosis of early cervical disc degeneration in adolescents and the area under the receiver operating characteristic curve were calculated. Results:T 2 value measured in each cervical intervertebral disc segment in the observation group was significantly greater than that in the control group ( t = 5.06, 4.47, 3.57, 2.93, 4.98 for C2-3, C3-4, C4-5, C5-6, C6-7 segments, all P < 0.05). In the observation group, the number of patients with Pfirrmann grade II cervical intervertebral disc degeneration was highest, accounting for 42% (21/50). There was a significant difference in cervical intervertebral disc segment T 2 value between different Pfirrmann disc grades ( t = 2.62, P = 0.018, vs. Pfirrmann disc grade I ; t = 2.12, P = 0.045, vs. Pfirrmann disc grade II; t = 2.24, P = 0.049, vs. Pfirrmann disc grade III). The higher Pfirrmann grade, the lower T 2 value of cervical intervertebral disc nucleus pulposus. The receiver operating characteristic curve showed that the sensitivity and specificity of T 2 value in the diagnosis of early cervical disc degeneration and the area under the receiver operating characteristic curve were 81.2%, 79.8% and 0.756, respectively. Conclusion:T 2 mapping imaging technology can predict early cervical intervertebral disc degeneration in adolescents by quantitatively analyzing the T 2 value of cervical intervertebral disc nucleus pulposus and has a high value in the diagnosis of cervical intervertebral disc degeneration. This achievement is of innovation and science.