摘要目的:分析Brock模型及肺部结节CT报告分级系统（LU-RADS）对肺结节良恶性的鉴别诊断价值。方法:回顾性分析金华广福医院2021年3月至2022年3月收治的肺结节患者84例的临床资料，根据病理检查结果将其分为良性组（ n=26）和恶性组（ n=58）。比较两组的Brock模型参数及LU-RADS分类的差异，分析Brock模型及LU-RADS对肺结节良恶性的鉴别诊断价值。 结果:恶性组Brock模型参数中年龄、结节直径、结节周围出现毛刺征、结节成分为混合性磨玻璃、多发性结节占比及恶性概率分别为（56.25±4.15）岁、（14.65±2.35）mm、44.8%、77.6%、51.7%、（0.26±0.11），良性组分别为（47.35±3.56）岁、（8.92±1.65）mm、15.4%、53.8%、26.9%、（0.05±0.02），两组差异均有统计学意义（ t=9.48、11.18，χ 2=6.78、4.84、4.48， t=9.63，均 P < 0.05）；恶性组LU-RADS分类下恶性结节占比为79.3%，高于良性组的42.3%（χ 2=11.27， P < 0.05）。经受试者工作特征曲线（ROC曲线）分析，Brock模型对肺结节良恶性的鉴别诊断价值优于LU-RADS。 结论:相较于LU-RADS，鉴别诊断肺结节良恶性时应用Brock模型的价值更高，临床可优先使用该评估方法。

abstractsObjective:To investigate the value of Brock model and the Lung Reporting and Data System (LU-RADS) in the differential diagnosis of benign and malignant pulmonary nodules.Methods:A total of 84 patients with pulmonary nodules who received treatment at Zhejiang Jinhua Guangfu Tumor Hospital from March 2021 to March 2022 were retrospectively included in this study. The patients were divided into a benign group ( n = 26) and a malignant group ( n = 58) based on their pathological examination results. The Brock model parameters and LU-RADS classification were compared between the two groups. The value of the Brock model and the LU-RADS in the differential diagnosis of benign and malignant pulmonary nodules was analyzed. Results:In the malignant group, the the Brock model parameters including age, nodule diameter, the presence of spicule signs surrounding the nodule, the composition of mixed ground glass nodules, the proportion of multiple nodules, and the probability of malignancy were (56.25 ± 4.15) years, (14.65 ± 2.35) mm, 44.8%, 77.6% , 51.7%, and (0.26 ± 0.11), respectively. These parameters were (47.35 ± 3.56) years, (8.92 ± 1.65) mm, 15.4%, 53.8%, 26.9%, and (0.05 ± 0.02) in the benign group. There were significant differences in these parameters between the two groups ( t = 9.48, 11.18, χ2 = 6.78, 4.84, 4.48, t = 9.63, all P < 0.05). The proportion of malignant nodules under LU-RADS classification in the malignant group was 79.3%, which was significantly higher than 42.3% in the benign group ( χ2 = 11.27, P < 0.05). According to the Receiver Operating Characteristic (ROC) curve, the Brock model outperformed LU-RADS in the differential diagnosis of benign and malignant pulmonary nodules. Conclusion:Compared with LU-RADS classification, the Brock model demonstrates higher value in the differential diagnosis of benign and malignant pulmonary nodules, and this evaluation method can be prioritized in clinical practice.