摘要限食疗法在防治代谢性疾病领域受到广泛重视，限食后，多种食欲调节激素发生变化，如瘦素、胰岛素、胰淀素的降低，肽YY、胰高血糖素样肽1、胰多肽的升高，这些变化在调节人体摄食过程、改善糖脂代谢、维持能量平衡等方面具有重要作用。笔者就限食疗法对食欲调节激素的相关影响，深入探讨限食疗法治疗代谢性疾病的作用机制，为肥胖、2型糖尿病等代谢性疾病的长期缓解提供防治思路。

abstractsCalorie restriction has garnered significant attention in the prevention and treatment of metabolic diseases. During calorie restriction, various appetite-regulating hormones undergo changes, including a decrease in leptin, insulin, and amylin, along with an increase in peptide YY, glucagon-like peptide 1, and pancreatic polypeptide. These hormonal changes play a crucial role in regulating the body's feeding processes, improving glucose and lipid metabolism, and maintaining energy balance. In this paper, we discuss the effects of dietary restriction therapy on appetite-regulating hormones and the mechanisms by which this therapy aids in the treatment of metabolic diseases. Our goal is to provide insights for the prevention and long-term management of metabolic disorders such as obesity and type 2 diabetes.