摘要目的 探讨梭形细胞肿瘤临床病理与免疫组化特性及病理诊断.方法 应用免疫组化对34例梭形细胞肿瘤进行回顾性分析.结果 梭形细胞肉瘤17例占50%,梭形细胞癌肉瘤10例占26.47%,梭形细胞癌5例占14.70%,其他诊断2例占9.83%.免疫组化31例表达Vim,21例表达CK,14例表达EMA、Actin,8例表达CD117、S-100,7例表达CEA、SM、CD34.CK与Vim同时表达18例,分别表达8例,Vim与CD117同时表达8例,仅CK、EMA、CEA表达3例.结论 不同部位的梭形细胞肿瘤,形态学有其病理组织学特征,免疫组化同一梭形细胞肿瘤可有不同或相同抗体表达,不同类型梭形细胞肿瘤可有相同抗体表达,灶性表达非上皮组织来源肿瘤多由分化或转分化而来,结合免疫组化检测可提高病理诊断准确率.

abstractsObjective To discuss the spindle-shaped cell tumor clinical pathology and the immunohis tochemistry characteristic and the pathological diagnosis.Methods Corried immunohistochemistry on the review analysis to 34 example spindle-shaped cell tumor.Results The spindle-cell sarcoma 17 examples accounted for 50%,the spindle-shaped cell sarcocarcinoma 10 examples accounted for 26.47%,the spindle-shaped cell cancer 5 examples accounted for 14.70%,other diagnose 2 examples to accounted for 9.83%.Immunohistochemistry 31 examples express the Vim,21 example to express the CK,14 example to express EMA,the Actin,8 example express CD117,the S-100,7 example express CEA,SM,CD34.CK and Vim simultaneously express 18 examples,expresses 8 examples separately,Vim and CD117 simultaneously expresses 8 examples,only CK,EMA,CEA express 3 examples.Conclusion The different spot spindle-shaped cell tumor,the morphology has its his topathology characteristic,The Immunohistochemistry identical spindle-shaped cell tumor may have different or the same immune body expression,the different type spindle-shaped cell tumor may have the same immune body expression,the stove expression non-epithelial tissue originates the tumor many comes by the differentiation or the transdifferentiatian,the union immunity group examination may enhance the pathological diagnosis rate of accuracy.