摘要目的 探讨血清癌抗原153(CA153)、组织多肽特异性抗原(TPS)和癌抗原125(CA125)联合检测对乳腺癌诊断的临床应用价值.方法 采用电化学发光法检测患者血清中CA153、TPS、CA125.结果 乳腺癌患者组血清三种标记物水平及阳性率均明显高于乳腺良性病变组和正常对照组(P＜0.01),联合检测的敏感性和诊断准确性均比单项检测高.结论 联合检测血清中的CA153、TPS、CA-125对乳腺癌的早期诊断具有重要价值.

abstractsObjective To explore the clinical significance of combined detection of serum CA153,TPS,CA125 in the diagnosis of breast cancer. Methods Technique of electrochem ilum inescence immunoassay was used to mesure serum CA153,TPS and CA125 levels. Results The levels and the positive rates of three kinds of markers in breast cancer patients were significantly higher than those of mammary benign patients and normal controls (P ＜ 0. 01) , The diagnostic sensitivity and accuracy of combined detection were higher than that of single assay. Conclusion The combined detection of serum CA153,TPS, CA125 levels has important clinical significance in the diagnosis of breast cancer.