摘要目的 探讨认知行为干预对炎症性肠病(IBD)伴情绪障碍患者心理状态和生活质量的影响.方法 对符合2000年成都会议诊断标准且伴情绪障碍的45例IBD患者随机分为两组,对照组(n=22)给予常规治疗;研究组(n=23)在常规对症治疗的基础上给予认知行为干预;10周为1疗程.于入组时、10周末采用焦虑自评量表(SAS)、抑郁自评量表(SDS)、健康状况调查问卷(SF-36)对两组患者进行心理状态和生活质量评定.结果 10周末研究组SAS和SDS评分比入组时均显著降低[分别为(47.11±8.82,38.25±9.33);(48.13±9.33),(41.28±7.13)](P＜0.01,P＜0.01);治疗后研究组与对照组比较[分别为(38.25±9.33),(45.31±6.30);(41.28±7.1),(46.43±8.06)](P＜0.01,P＜0.05).研究组患者治疗前后SF-36各分量表值差异均有显著性(P＜0.05);治疗后研究组与对照组表值比较除SF一项外均有显著性差异(P＜0.05).结论 认知行为干预有助于改善炎症性肠病患者的心理状态,提高患者的生活质量.

abstractsObjective To investigate the effect of the Cognition behavior intervention on the mental status and the quality of life of patients with inflammatory bowel disease with mood disorders. Methods 45 patients with inflammatory bowel disease (IBD) who diagnosed by year 2000 chengdu IBD conference diagnostic code with mood disorders were randomly divided into two groups: the study group( n = 23 ) and the control group (n =22). The two groups had the same clinical routine treatments for 10 weeks as 1 course of treatment, and Cognition behavior intervention was added to the study group. The Self-Rating Anxiety Scale (SAS), self-rating depressive scale (SDS) were analyzed on mental status, and the health status was compared by SF-36 before and after 10 weeks of treatment respectively. Results The scores of SAS and SDS scores of the study group after the treatment notably dropped [ SAS: ( 47. 11 ± 8. 82 ), ( 38.25 ± 9. 33 ), P ＜ 0. 01; SDS: ( 48.13 ± 9. 33 ),(41.28 ±7.13) ,P ＜0. 01 ] ,and compared to the control group [SAS: (38.25 ±9. 33), (45.31 ±6. 30) ,P ＜0.01; SDS: (41.28 ± 7. 1 ), (46.43 ± 8.06 ), P ＜ 0. 05 ], while The scores on each factors of SF-36 of the study group were significantly altered before and after treatment( P ＜ 0. 05 ) ;so was the other factors except the SF score of measuring scale on quality of life of the two groups. Conclusion Cognition behavior intervention plays an important role in the treatment of patient with inflammatory bowel disease to improve their mental status and quality of life.