摘要目的 探讨基于临床护理路径的营养支持对阿尔茨海默病(AD)患者营养状况和生活质量的影响.方法 连续选取符合研究标准的老年AD患者101例,随机分为研究组(n=51)或对照组(n=50),分别接受为期2个月的基于临床护理路径的营养支持(研究组)或常规营养支持(对照组).分别使用营养风险筛查2002(NRS 2002)和AD生活质量评分量表(QOL-AD)在营养支持前后进行营养风险筛查和生活质量评分,比较两组干预前后营养状况和生活质量.结果 两组患者基线值具可比性(所有P>0.05).营养支持2个月后,与对照组比较,研究组营养风险(17.6％vs 36.0％,P=0.037)和营养不足(9.8％vs 26.0％,P=0.033)的发生率显著降低;生活质量评分显著提高[(35.73±5.85)分vs(30.76±6.14)分,P=0.023].结论 基于临床护理路径的营养支持有助于改善老年AD住院患者的营养状况和生活质量.

abstractsObjective To explore the effect of nutritional support based on clinical nursing pathway on nutritional status and quality of life among elderly inpatients with Alzheimer disease (AD). Methods A total of 101 elderly inpatients with AD who met the criteria of the protocol were consecutively enrolled and randomly divided to study group receiving nutritional support based on clinical nursing pathway for two months (n = 51) and control group receiving routine nutritional management for 2 months (n =50). Nutritional risk and quality of life were measured by nutritional risk screening 2002 (NRS 2002) and Quality of Life-Alzheimer's Disease Scale (QOL-AD) respectively before and after nutritional support. Results Baseline data were comparable between the two groups (all P>0. 05). After 2-month nutritional support, compared to the control, the incidence of nutritional risk (36. 0％ vs 17. 6％, P = 0. 037) and undernutrition (26. 0％ vs 9. 8％, P = 0. 033) decreased significantly in study group. The score of quality of life in study group were significant higher than that of control group (35. 73±5. 85 vs 30. 76±6. 14, P = 0. 023). Conclusion The nutritional support based on clinical nursing pathway is helpful to improve the nutritional status and quality of life in elderly hospitalized patients with AD.