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Electric stimulation and decimeter wave therapy improve the recovery of injured sciatic nerves

摘要Drug treatment, electric stimulation and decimeter wave therapy have been shown to promote the repair and regeneration of the peripheral nerves at the injured site. This study prepared a Mackin-non’s model of rat sciatic nerve compression. Electric stimulation was given immediately after neurolysis, and decimeter wave radiation was performed at 1 and 12 weeks post-operation. Histo-logical observation revealed that intraoperative electric stimulation and decimeter wave therapy could improve the local blood circulation of repaired sites, al eviate hypoxia of compressed nerves, and lessen adhesion of compressed nerves, thereby decreasing the formation of new entrapments and enhancing compressed nerve regeneration through an improved microenvironment for rege-neration. Immunohistochemical staining results revealed that intraoperative electric stimulation and decimeter wave could promote the expression of S-100 protein. Motor nerve conduction velocity and amplitude, the number and diameter of myelinated nerve fibers, and sciatic functional index were significantly increased in the treated rats. These results verified that intraoperative electric stimulation and decimeter wave therapy contributed to the regeneration and the recovery of the functions in the compressed nerves.

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作者单位 Department of 0rthopedics, the First Hospital of Hebei Medical University, Shijiazhuang 050031, Hebei Province, China [1] Department of Hand Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei Province, China [2]
栏目名称 Research and Report Articles
DOI 10.3969/j.issn.1673-5374.2013.21.006
发布时间 2013-09-23
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中国神经再生研究(英文版)

中国神经再生研究(英文版)

2013年21期

1974-1984页

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