A brief review of recent advances in stem cell biology

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摘要Stem cells have the remarkable potential to develop into many different cell types, essentially with-out limit to replenish other cells as long as the person or animal is still alive, offering immense hope of curing Alzheimer’s disease, repairing damaged spinal cords, treating kidney, liver and lung diseases and making damaged hearts whole. Until recently, scientists primarily worked with two kinds of stem cells from animals and humans:embryonic stem cells and non-embryonic“somatic”or“adult”stem cells. Recent breakthrough make it possible to convert or“reprogram”specialized adult cells to assume a stem stem-like cells with different technologies. The review will brielfy dis-cuss the recent progresses in this area.

作者单位 Stark Neuroscience Research Institute and Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, IN, USA ^[1] Guangdong-Hongkong-Macau Institute of CNS Regeneration GHMICR, Jinan University, Guangzhou, Guangdong Province, China ^[2] Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China ^[3]

关键词 stem cell adult stem cell embryonic stem cell somatic cell nuclear transfer induced plu-ripotent stem cell stimulus-triggered acquisition of pluripotency

栏目名称 PERSPECTIVES

DOI 10.4103/1673-5374.131565

发布时间 2014-05-21

基金项目

The study was supported by NIH/NINDS R01-NS043246, P30-NS045758, the Interna-tional Spinal Research Trust the Ohio State University College of Medicine

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