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Decoding degeneration:the implementation of machine learning for clinical detection of neurodegenerative disorders

摘要Machine learning represents a growing subfield of artificial intelligence with much promise in the diagnosis,treatment,and tracking of complex conditions,including neurodegenerative disorders such as Alzheimer's and Parkinson's diseases.While no definitive methods of diagnosis or treatment exist for either disease,researchers have implemented machine learning algorithms with neuroimaging and motion-tracking technology to analyze pathologically relevant symptoms and biomarkers.Deep learning algorithms such as neural networks and complex combined architectures have proven capable of tracking disease-linked changes in brain structure and physiology as well as patient motor and cognitive symptoms and responses to treatment.However,such techniques require further development aimed at improving transparency,adaptability,and reproducibility.In this review,we provide an overview of existing neuroimaging technologies and supervised and unsupervised machine learning techniques with their current applications in the context of Alzheimer's and Parkinson's diseases.

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作者 Fariha Khaliq [1] Jane Oberhauser [2] Debia Wakhloo [3] Sameehan Mahajani [4] 学术成果认领
作者单位 Department of Biomedical Engineering and Sciences(BMES),National University of Science and Technology,Islamabad,Pakistan [1] Department of Neuropathology,School of Medicine,Stanford University,Stanford,CA,USA [2] Department of Neuropathology,School of Medicine,Stanford University,Stanford,CA,USA;Levitas Bio,Menlo Park,CA,USA [3] Department of Neuropathology,School of Medicine,Stanford University,Stanford,CA,USA;CODA biotherapeutics,South San Francisco,CA,USA [4]
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发布时间 2022-11-28(万方平台首次上网日期,不代表论文的发表时间)
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中国神经再生研究(英文版)

中国神经再生研究(英文版)

2023年18卷6期

1235-1242页

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