换一批Star power:harnessing the reactive astrocyte response to promote remyelination in multiple sclerosis
摘要Astrocytes are indispensable for central nervous system development and homeostasis.In response to injury and disease,astrocytes are integral to the immunological-and the,albeit limited,repair response.In this review,we will examine some of the functions reactive astrocytes play in the context of multiple sclerosis and related animal models.We will consider the heterogeneity or plasticity of astrocytes and the mechanisms by which they promote or mitigate demyelination.Finally,we will discuss a set of biomedical strategies that can stimulate astrocytes in their promyelinating response.
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关键词
astrocytesdemyelinationdrug-based therapiesmyelin repairoligodendrocyte precursor cellsreactive astrogliosis
栏目名称
DOI
10.4103/1673-5374.380879
发布时间
2023-12-29（万方平台首次上网日期，不代表论文的发表时间）
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