Epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China:a hospital-based retrospective study

二维码有效期 120s

摘要Traumatic spinal cord injury is potentially catastrophic and can lead to permanent disability or even death.China has the largest population of patients with traumatic spinal cord injury.Previous studies of traumatic spinal cord injury in China have mostly been regional in scope;national-level studies have been rare.To the best of our knowledge,no national-level study of treatment status and economic burden has been performed.This retrospective study aimed to examine the epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China at the national level.We included 13,465 traumatic spinal cord injury patients who were injured between January 2013 and December 2018 and treated in 30 hospitals in 11 provinces/municipalities representing all geographical divisions of China.Patient epidemiological and clinical features,treatment status,and total and daily costs were recorded.Trends in the percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department and cost of care were assessed by annual percentage change using the Joinpoint Regression Program.The percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department did not significantly change overall(annual percentage change,-0.5%and 2.1%,respectively).A total of 10,053(74.7%)patients underwent surgery.Only 2.8%of patients who underwent surgery did so within 24 hours of injury.A total of 2005(14.9%)patients were treated with high-dose(≥500 mg)methylprednisolone sodium succinate/methylprednisolone(MPSS/MP);615(4.6%)received it within 8 hours.The total cost for acute traumatic spinal cord injury decreased over the study period(-4.7%),while daily cost did not significantly change(1.0%increase).Our findings indicate that public health initiatives should aim at improving hospitals'ability to complete early surgery within 24 hours,which is associated with improved sensorimotor recovery,increasing the awareness rate of clinical guidelines related to high-dose MPSS/MP to reduce the use of the treatment with insufficient evidence.

作者 Hengxing Zhou ^[1] Yongfu Lou ^[2] Lingxiao Chen ^[3] Yi Kang ^[4] Lu Liu ^[5] Zhiwei Cai ^[6] David B.Anderson ^[7] Wei Wang ^[8] Chi Zhang ^[8] Jinghua Wang ^[9] Guangzhi Ning ^[4] Yanzheng Gao ^[10] Baorong He ^[5] Wenyuan Ding ^[11] Yisheng Wang ^[12] Wei Mei ^[13] Yueming Song ^[14] Yue Zhou ^[15] Maosheng Xia ^[16] Huan Wang ^[17] Jie Zhao ^[18] Guoyong Yin ^[19] Tao Zhang ^[20] Feng Jing ^[21] Rusen Zhu ^[22] Bin Meng ^[23] Li Duan ^[24] Zhongmin Zhang ^[25] Desheng Wu ^[26] Zhengdong Cai ^[27] Lin Huang ^[28] Zhanhai Yin ^[29] Kainan Li ^[30] Shibao Lu ^[31] Shiqing Feng ^[32] 学术成果认领

作者单位 Department of Orthopedics,The Second Hospital,Cheeloo College of Medicine,Shandong University,Shandong,China;Department of Orthopedics,Shandong University Center for Orthopedics,Qilu Hospital,Cheeloo College of Medicine,Shandong University,Shandong,China ^[1] Department of Orthopedics,The Second Hospital,Cheeloo College of Medicine,Shandong University,Shandong,China;Department of Orthopedics,Tianjin Medical University General Hospital,International Science and Technology Cooperation Base of Spinal Cord Injury,Tianjin Key Laboratory of Spine and Spinal Cord,Tianjin,China ^[2] Department of Orthopedics,Shandong University Center for Orthopedics,Qilu Hospital,Cheeloo College of Medicine,Shandong University,Shandong,China;Faculty of Medicine and Health,The Back Pain Research Team,Sydney Musculoskeletal Health,The Kolling Institute,University of Sydney,Sydney,NSW,Australia ^[3] Department of Orthopedics,Tianjin Medical University General Hospital,International Science and Technology Cooperation Base of Spinal Cord Injury,Tianjin Key Laboratory of Spine and Spinal Cord,Tianjin,China ^[4] Department of Spine Surgery,Honghui Hospital,Xi'an Jiaotong University,Xi'an,Shaanxi Province,China ^[5] Department of Burns and Plastic Surgery,The Fourth Medical Center of Chinese PLA General Hospital,Beijing,China ^[6] Faculty of Medicine and Health,School of Health Sciences,University of Sydney,NSW,Australia;Sydney Spine Institute,Burwood,Sydney,NSW,Australia ^[7] Department of Orthopedics,Shandong University Center for Orthopedics,Qilu Hospital,Cheeloo College of Medicine,Shandong University,Shandong,China ^[8] Laboratory of Epidemiology,Tianjin Neurological Institute,Department of Neurology,Tianjin Medical University General Hospital&Tianjin Neurological Institute,Key Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous System,Ministry of Education and Tianjin City,Tianjin,China ^[9] Department of Orthopedics,Henan Provincial People's Hospital,Zhengzhou,Henan Province,China ^[10] Department of Spinal Surgery,The Third Hospital of Hebei Medical University,Shijiazhuang,Hebei Province,China ^[11] Department of Orthopedics,The First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan Province,China ^[12] Department of Spine Surgery,Zhengzhou Orthopedics Hospital,Zhengzhou,Henan Province,China ^[13] Department of Orthopedic Surgery and Orthopedic Research Institute,West China Hospital,Sichuan University,Chengdu,Sichuan Province,China ^[14] Department of Orthopedics,Xinqiao Hospital,Army Medical University,Chongqing,China ^[15] Department of Orthopedics,The First Affiliated Hospital of China Medical University,Shenyang,Liaoning Province,China ^[16] Department of Spinal Surgery,Shengjing Hospital of China Medical University,Shenyang,Liaoning Province,China ^[17] Shanghai Key Laboratory of Orthopedic Implants,Department of Orthopedic Surgery,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,China ^[18] Department of Orthopedics,The First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu Province,China ^[19] Department of Spinal Surgery,Shanghai Jiao Tong University Affiliated Sixth People's Hospital,Shanghai,China ^[20] Department of Spinal Surgery,Tianjin Hospital,Tianjin,China ^[21] Department of Spine Surgery,Tianjin Union Medical Center,Tianjin,China ^[22] Department of Orthopedic Surgery,The First Affiliated Hospital of Soochow University,Suzhou,Jiangsu Province,China ^[23] Department of Orthopedics,Shenzhen Intelligent Orthopedics and Biomedical Innovation Platform,Guangdong Artificial Intelligence Biomedical Innovation Platform,Shenzhen Second People's Hospital,The First Affiliated Hospital of Shenzhen University Health Science Center,Shenzhen,Guangdong Province,China ^[24] Department of Orthopedics,The Third Affiliated Hospital of Southern Medical University,Guangzhou,Guangdong Province,China ^[25] Department of Spine Surgery,Shanghai East Hospital Affiliated to Tongji University School of Medicine,Shanghai,China ^[26] Department of Orthopedics,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,China ^[27] Department of Orthopedics,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou,Guangdong Province,China ^[28] Department of Orthopedics,The First Affiliated Hospital,Xi'an Jiaotong University,Xi'an,Shaanxi Province,China ^[29] Department of Orthopedic Surgery,Affiliated Hospital of Chengdu University,Chengdu,Sichuan Province,China ^[30] Department of Orthopedics,Beijing Xuanwu Hospital,Capital Medical University,Beijing,China ^[31] Department of Orthopedics,The Second Hospital,Cheeloo College of Medicine,Shandong University,Shandong,China;Department of Orthopedics,Shandong University Center for Orthopedics,Qilu Hospital,Cheeloo College of Medicine,Shandong University,Shandong,China;Department of Orthopedics,Tianjin Medical University General Hospital,International Science and Technology Cooperation Base of Spinal Cord Injury,Tianjin Key Laboratory of Spine and Spinal Cord,Tianjin,China ^[32]

关键词 China clinical features costs epidemiology methylprednisolone sodium succinate methylprednisolone retrospective study traumatic spinal cord injury treatment

栏目名称 Spinal Cord Injury and Neural Regeneration

DOI 10.4103/1673-5374.382257

发布时间 2023-12-26

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