摘要目的 评价准分子激光原位角膜磨镶术(laser in situ keratomileusis;LASIK)治疗近视性屈光参差性弱视的临床疗效.方法 用LASIK手术矫正8位近视性屈光参差性弱视患者,比较手术前后屈光不正的度数和立体视锐度的改变,并将术前的最佳矫正视力和术后第1天,第3天,第10天的裸眼视力以及6～9个月随访的裸眼视力和最佳矫正视力进行比较和分析.结果 术前屈光度数高眼的屈光不正的等效球镜平均为(-10.06±1.50)D,术后该眼屈光不正的等效球镜平均为(0.19±0.32)D.手术前后立体视锐度差别有统计学意义(z=-2.207,P=0.027).术前屈光度数高眼矫正视力和术后该眼矫正视力相比,差别有统计学意义(F=11.431;P=0.000).结论 LASIK手术能安全,有效地减少近视性屈光参差,提高患者的视力和立体视功能.

abstractsObjective To evaluate the clinical effect of laser in situ keratomileusis (LASIK) for my- opic anisometropic amblyopia. Methods LASIK was performed in 8 myopic anisometropic amblyopia pa- tients, the mean preoperative and postoperative spherical equivalent refraction and stereo acuity were compared. Preoperative best spectacle corrected visual acuity and postoperativelday, 3day, 10day uncorrected visual acu- ity and 6-9month following-up uncorrected visual acuity and best spectacle corrected visual acuity were com- pared and analyzed. Results The mean preoperative spherical equivalent refraction was -10.06D±1.50D,after LASIK,the mean postoperative spherical equivalent refraction was0.19D±0.32D. The improvement in stereo acuity was statistically significant (z=-2.207, P=0.027).On general, the improvement of postoperative uncor- rected visual acuity was statistically significant (F=11.431; P =0.000).Conclusion Laser in situ keratomilens can reduce myopic anisometropia safely and effectively. It can improve visual acuity and stereo acuity also.