摘要目的 探讨相干光生物测量法在儿童眼球生物测量中的重复性和准确性,评价该方法在儿童中的应用价值.方法 用ZeissIOL-Master3.02相干光生物测量仪(PCI)、QMC5.03接触式A型超声生物测量仪(A超)和TopconKR-8800角膜曲率计分别测量小儿眼科门诊患者126例244只眼的眼球轴长(Ax)、前房深度(ACD)和角膜曲率(K值).其中男51例,女75例,平均年龄(10.7±2.9)岁(3～16岁).全部患者排除眼部器质性病变,检查静态屈光.结果 PCI和A超测量的Ax的变异系数(COV)分别为0.67%和0.72%,PCI测量的Ax和ACD分别比A超测量值大(0.22±0.22)mm和(0.10±0.20)mm,差异均有统计学意义,P<0.05.PCI与A超测量结果显著相关,相关系数分别为0.98(Ax)和0.64(ACD),P<0.05.PCI与曲率计测量的K值相比,差别为0.04D,无统计学意义,P>0.05.结论 PCI测量儿童眼球生物参数稳定可靠,与A超的测量结果高度相关,可重复性高于A超.PCI测量的K值与曲率计测量结果无差异.PCI可以替代A超和曲率计,有望成为儿童眼球生物测量的常规方法.

abstractsObjective To evaluate the repeatability and accuracy of partial coherence interferometry on the ocular biometry of children by comparing it with ultrasonic biometry and auto-keratometry.Methods Zeiss IOL-Master3.02, QMC5.03 ultrasonic A-scan and Topcon KR-8800 auto-keratometry are used sequen-tially in a group of children which contains 126 cases (244 eyes)with average age (10.7±2.9)years (3～16 years).Results The coefficient of variation(COV)of PCI and A-scan on the measurement of Ax were 0.67% and 0.72%,respectively.The Ax and ACD values were significantly larger with PCI (P<0.05)than with A-scan, with the differences of 0.22±0.22mm and 0.10±0.20mm, respectively.PCI is significantly correlated with A-scan on the measurement of Ax (r=0.98)and ACD (r=0.64).The keratometric readings of PCI and au-to-keratometry aren't significantly different (P>0.05).Conclusions PCI is a useful method on the ocular biometry of children with repeatability higher than A-scan.PCI can be an alternative method on routine ocular biometry of children instead of A-scan and auto-keratometry.