摘要目的 探讨角膜波前像差联合Q值优化的非球面切削准分子激光上皮下角膜切削术(LASEK)与角膜波前像差联合Q值优化的非球面切削准分子激光原位角膜磨镶术(LASIK),分别治疗角膜薄(<500μm)和角膜厚(>500μm)的高度近视的临床疗效比较.方法 选取角膜厚度薄的高度近视患者行LASEK治疗25例(42只眼),角膜厚的高度近视患者38例(65只眼),比较术前视力、年龄、角膜厚度、切削厚度、剩余角膜厚度、等效球镜度、球差、慧差、总阶像差,术后2周,4周,3月,6月的视力,比较术后6月两组视力、等效球镜度、球差、慧差、总阶像差、HAZE等级.结果 两种手术方式术后6月内的视力,术后6月的等效球镜度、球差、慧差、总阶像差均无统计学意义,治疗高度近视具有相同均具有很高的安全性、有效性及可预测性且两组具有相同的临床疗效.结论 非球面切削的LASEK治疗角膜薄的高度近视与非球面切削的LASIK治疗角膜厚的高度近视具有相同的临床疗效.

abstractsObjective To compare the clinical curative effect of corneal wavefront-guided combining Q-value guided aspheric keratctomy excimer LASEK for high myopia of thin cornea (<500μm) and corneal wavefront-guided combining Q-value guided LASIK for high myopia of thick cornea (>500μm). Methods Of selected 25 high myopia of thin cornea (42 eyes), and 38 high myopia of thick cornea (65 eyes), compared the preoperative uncorrected visual acuity (UCVA), age, corneal thickness, atherectomy thickness,remnant thickness, spherical equivalent (SE), Coma-like RMS (root of mean square), spherical-like RMS,RMSg (root of mean square of general aberration) with postoperative UCVA of 2, 4 weeks, 1 month, 3, 6 months SE, Coma-like RMS, spherical-like RMS, RMSg, Level of Haze. Results There were no statistically significant differences between two groups 6 months aiter operation in UCVA, spherical equivalent (SE),Coma-like RIMS, spherical-like RMS and RMSg. Both groups showed high safety, efficacy, predictability and the same clinical curative effect. Conclusions Aspheric keratectomy excimer LASEK for high myopia of thin cornea and corneal wavefront-guided combining Q-value guided LASIK for high myopia of thick cornea have the same clinical curative effect.