摘要目的 探讨克罗恩病手术患者蒙特利尔分型的临床特点.方法 回顾分析43例克罗恩病手术患者(手术组)的临床资料,按蒙特利尔分型标准进行临床分型,对比非手术的克罗恩病患者(非手术组)125例各亚型的临床特征.结果 手术组17-40岁(A2)28例(65.1%),大于40岁(A3)者14例(32.6%),16岁以下(A1)者只有1例;与非手术组比较,差异无统计学意义(P>0.05).手术组病变累及回肠末端(L1)18例(41.9%).结肠(L2)11例(25.6%),回结肠(L3)13例(30.2%),上消化道(L4)1例(2.3%);与非手术组比较,差异也无统计学意义(P>0.05).疾病行为:手术组无狭窄无穿透(B1)1例(2.3%),狭窄(B2)26例(60.5%),穿透(B3)16例(37.2%);与非手术组的B1亚型79例(63.2%)、B2亚型44例(35.2%)和B3亚型2例(1.6%)相比,差异有统计学意义(P=0.000、P=0.004和P=0.000).结论 克罗恩病手术患者的年龄和病变部位的亚型与非手术患者相同,但其疾病行为主要为狭窄和穿透亚型,是手术治疗的主要原因.

abstractsObjective To investigate the clinical features of Crohn disease according to the Montreal classification. Methods Clinical data of 43 surgical patients with Crohn disease (surgical group) and 125 non-surgical patients with Crohn disease (non-surgical group) were retrospectively analyzed and compared between two groups. The Montreal classification was used. Results In the surgical group, 28 patients(65.1%) were A2, 14(32.6%) were A3 and only one was A1, which was not significantly different as compared to the non-surgery group. The proportions of L1, L2, L3, and L3 subtype in the surgical group were 41.9%, 25.6%, 30.2%, and 2.3%, respectively, which was not significantly different as compared to that in the non-surgery group. In the surgical group, B1 disease was found in 1 case(2.3%), B2 in 26 cases(60.5%), and B3 in 16 cases(37.2%), while in the non-surgical group, B1 was found in 79 cases (63.2%), B2 in 44 cases (35.2%) and B3 in 2 cases (1.6%).Differences were significant between two groups in disease behavior(P=0.001, P=0.004, P=0.001).Conclusions Most surgical patients of Crohn disease are A2. LI and L3 are the main lesion location.As disease behavior, B2 and B3 are the main reasons for operation.