中低位直肠癌环周切缘的规范化检测及研究进展
Standardized examination and research advancement of circumferential resection margin in patients with middle-lower rectal cancer
摘要随着TME技术和术前新辅助治疗的推广,直肠癌的预后在逐步改善.环周切缘(CRM)是目前直肠癌预后的重要影响因素之一.CRM阳性将导致预后不良.明确CRM阳性的不同种类、定义和影响因素有现实意义.直肠癌病理学中的TME质量控制和CRM判断的标准非常重要.完整切除肛提肌的扩大经腹会阴联合切除术(APR)即柱状APR较传统APR在降低CRM阳性率方面可能有一定优势.
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abstractsThe introduction of total mesorectal excision and the use of neoadjuvant therapy has led to improved prognosis of rectal cancer. Circumferential resection margin (CRM) is one of the main prognostic factors. Positive CRM is associated with adverse prognosis. It is of clinical significance to clarify different patterns of CRM involvement,the exact definitions, and associated factors. TME quality assessment and accurate determination of CRM involvement are crucial in the pathologic examination of rectal cancer.Extended abodminoperineal resection during which the levator muscles are resected en bloc with the anus and lower rectum may be superior than conventional abdominoperineal resection (APR) in terms of obtaining a negative CRM.
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