摘要结直肠癌肝转移诊断和综合治疗领域近年来发展迅速，中国《结直肠癌肝转移诊断和综合治疗指南》（《指南》）也应运而生，旨在规范和提高我国结直肠癌肝转移的诊疗水平。本文通过解读2013版的《指南》内容，提出应该重视结直肠癌肝转移的相关基因检测，以用于指导个体化治疗；强调多学科团队在结直肠癌肝转移诊疗中的作用，并合理选择分子靶向药物。同时，就结直肠癌肝转移的手术时机选择、微创手术的应用和肝转移灶的局部治疗等方面进行了讨论。

abstractsIn recent years there have been great developments in the diagnosis and comprehensive treatment of colorectal cancer liver metastases (CRLM). Guidelines for the Diagnosis and Comprehensive Treatment of Colorectal Cancer Liver Metastases were compiled to standardize and improve the diagnosis and treatment outcomes in China. This paper summarizes the updated content in the Guideline (V.2013). We should conduct gene testing related to CRLM to guide individual treatment, emphasize the role of the multidisciplinary team, and select molecular targeted drugs reasonably. In addition, we discuss the operative timing of CRLM, minimally invasive operation and regional therapy of liver metastases.