摘要胃肠间质瘤(GIST)生物学行为多样,准确判断肿瘤的复发风险是一个至关重要的临床问题。 GIST复发危险度的评估体系已经经历了数次变革,但仍有改进和提升的空间。各种病理形态学指标、基因突变特征及其他分子标记物有望在不久的将来丰富到 GIST 危险度评估体系中去,在肿瘤个体化治疗的新形势下,GIST危险度的评估必将越来越多元化。
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abstractsThe biological behavior of gastrointestinal stromal tumor (GIST) is highly variable. To assess the risk of recurrence of the primary tumor accurately is a key challenge. The risk assessment system of GIST has experienced several revolutions. The present accepted risk stratification scheme is still to be consummated. The pathological morphological characteristics, mutational features, and other biomarkers are helpful to improve the risk assessment system. The risk assessment of GIST in the future will be more and more diversified.
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