胃癌术后辅助放疗的利与弊
Advantages and disadvantages of postoperative radiotherapy in locally advanced gastric cancer
摘要胃癌是全球最常见的恶性肿瘤之一。根治性手术切除仍然是治愈胃癌最重要的手段。放疗作为一种有效而无创的局部治疗手段,可以为局部晚期胃癌患者带来更多的生存益处。先进放射治疗技术的运用,可以进一步优化靶区,降低重要正常组织器官的受量,减轻不良反应的发生。伴随着放疗技术的不断进步和先进化疗药物的出现,同步放化疗在将来会在局部晚期胃癌的治疗中占据越来越重要的地位。本文从放疗的疗效与毒性两方面来谈及胃癌辅助放疗的利与弊。
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abstractsGastric cancer is one of the most common cancers worldwide. Radical surgery remains the cornerstone of the treatment, however, outcomes are poor. As an effective, non-invasive treatment modality, radiotherapy constitutes an important part of the comprehensive therapy for locally advanced gastric cancer. The improved target coverage and accuracy of intensity-modulated radiotherapy allow for selective sparing of critical structures and reduce toxicity. With the use of new anti-cancer drugs and the progression of radiotherapy techniques, chemoradiotherapy may be of value in the future. This paper discusses the advantages and disadvantages of adjuvant radiotherapy in gastric cancer based on efficacy and toxicity.
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