机器人辅助食管癌根治术近期疗效分析
Short-term outcomes of robot-assisted minimally invasive esophagectomy for esophageal cancer
摘要目的:探讨达芬奇机器人辅助食管癌根治术的安全性及近期疗效。方法回顾性分析2016年4—7月期间,于中山大学肿瘤防治中心胸外科接受达芬奇机器人辅助食管癌根治术(胸腹部联合手术加颈部吻合)治疗的17例患者的临床资料。结果全组患者年龄为44~83岁,其中6例为新辅助放化疗后手术,11例行单纯手术。全组患者均在机器人辅助下完成胸腹部手术,无中转开胸或开腹以及围手术期死亡的发生。术后病理分期:新辅助放化疗患者中有3例为病理完全缓解,ⅡA期2例,ⅡB期1例;单纯手术患者ⅠA期1例,ⅡA期3例,ⅡB期5例,ⅢA期1例,ⅢB期1例。平均手术时间为195(145~305) min,术中平均出血量为60(30~200) ml;平均清扫淋巴结数目为28(8~40)枚/例,R0切除率为100%。重症监护病房(ICU)住院中位时间为4.5(1~36) d,术后住院中位时间为15.2(9~45) d。有4例(23.5%)患者出现术后并发症,包括肺部并发症3例(17.6%),声嘶2例(11.8%),乳糜胸1例(5.9%),无吻合口瘘和心律失常等并发症的发生。结论达芬奇机器人辅助食管癌根治术安全可行,近期疗效满意。
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abstractsObjective To evaluate the feasibility, safety and short-term clinical outcomes of robot-assisted minimally invasive esophagectomy (RAMIE). Methods Clinical data of 17 patients with esophageal cancer who received RAMIE between April 2016 and July 2016 were analyzed retrospectively. Results The age of the patients ranged from 44 to 83. Six patients received neoadjuvant radiochemotherapy while 11 patients underwent surgery alone. All patients were performed by the robot-assisted thoraco-laparoscopic minimally invasive esophagectomy. In-hospital mortality was 0% . None was converted to open transthoracic or laparotomy approach. In the neoadjuvant radiochemotherapy group, 3 patients received pathological complete response while 2 patients were stage ⅡA and 1 patient was stageⅡB. In the surgery alone group , 1 patient was stage ⅠA, 3 patients were stage ⅡA, 5 patients were stageⅡB, 1 patient was stage ⅢA and 1 patient was stage ⅢB. The mean operation time was 195 minutes (range 145 to 305 minutes). The mean blood loss was 60 ml (range 30 to 200 ml). Mean lymph node harvest was 28 nodes. The rate of radical resection was 100%. Median ICU stay was 4.5 days (range 1 to 36 days), and median overall postoperative hospital stay was 15.2 days(range 9 to 45 days). Postoperative complication occurred in 4 (23.5%) patients, including 3 (17.6%) of lung lesion, 2 (11.8%) of hoarseness, 1 (5.9%) of chylothorax, while no anastomotic leakage and arrhythmia was observed. Conclusion RAMIE for esophageal cancer is feasible and safe with favorable early outcomes.
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