结直肠肿瘤外科医生的挑战——继发性卵巢肿瘤的发生、发展与对策
A challenge for colorectal surgeons: pathogenesis, progression and management of the secondary tumors of the ovary
摘要结直肠癌外科医师经常遇到发生于女性患者的继发性卵巢肿瘤(STO)这一临床难题,特别见于年轻女性。STO多为消化道来源,可能的转移途径包括淋巴转移、血行转移和腹膜种植转移等,分子分型及组织病理特征各不相同。正确鉴定STO的来源与特征尤为重要,应结合病史、组织病理学、免疫组织化学、分子生物学和影像学等多种手段明确。STO患者的整体预后较差,以手术为主的综合治疗可以使部分患者获益。STO目前尚无特异性的治疗手段,不轻易放弃是每一个临床医生应该了解的正确选择。
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abstractsA common clinical problem encountered by colorectal surgeons is the secondary tumors of the ovary (STO), particularly in young female patients. Most STO are from the digestive tract, and the known possible metastatic mechanisms include lymphatic, hematogenous, and intraperitoneal spreading. The molecular and histopathological characteristics of STO from different sites are diverse. It is particularly important to correctly identify the origin and feature of STO, which should be clarified by combining medical history, histopathology, immunohistochemistry, molecular biology, imaging and other means. The prognosis of patients with STO is poor in general. Comprehensive therapies based on surgical resection can benefit some patients. There is no specific treatment for STO at present, but not giving up easily on these patients is the right choice that every surgeon should understand.
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