摘要The modern molecular-genetic methods have been implementing actively into the medical practiee.They improve diagnostic accuracy,help to prognosticate the course of oncological diseases,optimize the results of prenatal diagnosis,decrease mothers' anxiety and improve the clinical outcomes of pregnancy.There are used the various traditional approaches e.g.cariotyping,FISH and more contemporary-real-time PCR,comparative genomic hybridization (CGH) or chromosomal microarray analysis (CMA),Quantitative Fluorescent PCR (QF-PCR). For expressing diagnosis of triploidy by 21st and 18th chromosomes there was used QFPCR technologies with the consequent quantative analysis on the automatic capillary microelectrophoresis on the microarrays Experion DNA1K.There was determined that diagnostic accuracy of QF-PCR was comparable with existing routine methods,but it had some advantages including expressity and could be recommended for implementation into practical medicine.