摘要目的 比较卒中后失语患者与非失语患者抑郁情绪的特征.方法 纳入70例卒中后失语患者和70例卒中后非失语患者.对失语组采用标准化汉语失语检查量表(Aphasia Battery of Chinese,ABC)进行失语评估,并用卒中后失语患者抑郁问卷(医院版)(Stroke Aphasic Depression Questionnaire Hospital Version,SADQ-H)比较卒中后失语患者和非失语患者的抑郁情绪.结果 失语组的SADQ-H总分[(22.03±9.55)分]显著高于非失语组[(16.81±10.47)分],差异有显著性(P＜0.01);卒中后失语患者在兴趣缺乏、乐趣丧失、社交回避、易怒、情绪低落、注意力下降等方面较卒中后非失语患者严重.失语组抑郁发生率[64.28%]高于非失语组[50.00%];失语组中完全性失语抑郁发生率最高[78.26%];经皮质混合性失语[62.5%]、Broca[61.53%]、Werincke[62.50%]发生率相近为[62.00%]左右;抑郁严重程度与失语严重程度相关,卡方分析差异有统计学意义(P＜0.01).结论 卒中后失语患者较非失语患者抑郁情绪的发生率高,尤其是完全性失语、经皮质混合性失语、Broca、Werincke等类型的失语患者,并且抑郁发生率与失语严重程度相关.

abstractsObjective To compare the characteristics of post-stroke depression in patients with and without aphasia.Methods Seventy patients on the first infarction with aphasia and 70 stroke patients without aphasia were recruited.The aphasia deficits in patients were evaluated by using the Aphasia Battery of Chinese ( Aphasia Battery of Chinese, ABC) .The Stroke Aphasic Depression Questionnaire Hospital Version ( Stroke Aphasic Depression Questionnaire Hospital Version, SADQ-H) was applied to analyze the depression in the two groups.Results The sore in SADQ-H of the aphasia group was significantly higher than the control group( (22.03 ±9.55 )vs ( 16.81 ± 10.47 ), P ＜ 0.01 ) .Loss interest, anhedonia, social avoidance, irritability, depression, decreased attention were more serious in patients with aphasia after stroke than that without aphasia.Compared with control group ,the incidence of depression in aphasia group was higher(64.28% vs 50.00% ).The incidence in different types of aphasia: the complete aphasia ( 78.26% ), transcortical mixed aphasia ( 62.50% ), Broca ( 61.53% ),Werincke (62.50%).There was significantly correlation between the incidence of depression and the severity of aphasia.Conclusion The incidence of depression in stroke patients with aphasia is high,especially who have complete aphasia, transcortical mixed aphasia, Broca and Werincke, and it closely relate to the severity of aphasia.