摘要目的 探讨精神分裂症患者攻击行为与敌意归因偏向和童年创伤的关系.方法 采用修改版外显攻击行为量表(MOAS)对135例精神分裂症患者进行攻击行为评估,将患者分为攻击组(58例)和非攻击组(77例),同时做中文版模棱两可、目的和敌意问卷( AIHQ-C)以及童年创伤问卷(CTQ)评估,分析童年创伤、敌意归因偏向与攻击行为间的关系.结果 攻击组患者AIHQ-C敌意偏向总分[(6.27±1.20)分]、责备偏向总分[(8.04±1.97)分]和攻击偏向总分[(6.17±1.02)分]均高于非攻击组患者[分别为:(5.90±0.97)分、(6.91±2.10)分、(5.59±1.04)分],差异具有统计学意义(P＜0.05～0.01).相关分析显示,精神分裂症患者AIHQ-C评分、CTQ总分和MOAS分两两间均呈正相关(r=0.171～0.350,P＜0.05～0.01)；回归分析显示,敌意归因偏向可直接预测患者攻击行为(β=0.342,P＜0.05),在童年创伤与攻击行为的关系中起完全中介作用.结论 精神分裂症患者的攻击行为与童年创伤经历及归因方式相关,童年创伤通过敌意归因偏向的中介作用对患者的攻击行为产生影响.

abstractsObjective To explore the relationship among the aggressive behavior,hostile attribution bias and childhood trauma in schizophrenic patients.Methods 135 schizophrenic patients were tested with Modified Overt Aggression Scale (MOAS),the Chinese-version of the Ambiguous Intentions Hostility Questionnaire (AIHQ-C) and Childhood Trauma Questionnaire (CTQ).According to the score of the MOAS,the patients were divided into the aggressive group ( n =58 ) and the non-aggressive group ( n =77 ).The hostile attribution bias and the childhood trauma were compared between the two groups,and correlation and hierarchical regression analysis were used to investigate the relationships of the variables.Results Compared with the non-aggressive patients,the aggressive patients had significantly higher AIHQ-C total hostility bias score (6.27 ± 1.20 vs 5.90 ± 0.97,P ＜0.05 ),total blame bias score (8.04 ± 1.97 vs 6.91 ± 2.10,P ＜ 0.01 ) and total aggression bias score ( 6.17 ±1.02 vs 5.59 ± 1.04,P ＜ 0.01 ).Correlation analysis showed that the MOAS score,AIHQ scores and the total score of CTQ were significantly positively correlated with each other ( r =0.171 ～ 0.350,P ＜ 0.05 ～0.01 ).Regression analysis indicated the hostile attribution bias directly predicted the aggressive behavior( β =0.342,P ＜0.05) and completely mediated the relationship between the childhood trauma and the aggressive behavior.Conclusion The aggressive behavior in schizophrenic patients is associated with the experience of childhood trauma and the attribution style.The childhood trauma indirectly influences the aggressive behavior by the mediating of the hostile attribution bias.