摘要目的 探讨频发室性早搏(Premature ventricular contractions,PVCs)患者生活质量状况,以及射频导管消融对患者生活质量的影响.方法 采用健康状况调查问卷(SF-36)评定并比较60例健康体检正常者、100频发房性早搏(atrial premature contractions,APCs)患者与120例频发室性早搏患者的生活质量;然后,观察120例频发室性早搏患者中接受射频导管消融的患者与单纯药物治疗的患者3个月末的室性早搏减少情况及生活质量状况.结果 SF-36结果显示,与频发房性早搏患者相比,120例频发室性早搏患者的生理功能、精神健康明显受损,躯体疼痛表现明显增高(P值:0.0002～0.0380),其生活质量状况明显低于健康对照组(P值:0.0001～ 0.0315);48例接受射频导管消融的频发室性早搏患者3个月后的室性早搏显著少于72例单纯药物治疗者(t=18.8682,P＜0.01),生活质量状况也显著好于单纯药物治疗的患者(F值:15.329～39.274,P＜0.01).结论 频发室性早搏明显影响患者的生活质量,射频导管消融能够控制或消除患者的频发室性早搏,显著改善频发室性早搏患者的生活质量.

abstractsObjective To investigate the quality of life (QOL) of patients with frequent premature ventricular contractions (PVCs) and the effects of radiofrequency catheter ablation (RFCA) on them.Methods 120 patients with frequent PVCs,100 cases with frequent APCs and 60 healthy persons were assessed by 36-Health survey questionnaire (SF-36) originally.Three months later,the QOL of 48 cases received RFCA and 72 cases with drug therapy were evaluated again by SF-36.Meanwhile,decrease of PVCs were also calculated between these two groups.Results The scores of physiological function and mental health in patients with PVCs were lower than that of cases with APCs,while the score of bodily pain in patients with PVCs was higher (P value:0.0002-0.0380).In addition,the quality of life in patients with frequent PVCs were worse than healthy control(P value:0.0001-0.0915).Three months later,PVCs in 48 cases with frequent PVCs received RFCA were much fewer than that of 72 cases with drug therapy (t=18.8682,P＜0.01),and the quality of life in the former was much better than the latter (F=15.329-39.274,P＜0.01).Conclusion Frequent PVCs can deteriorate the patients' quality of life.RFCA can control or eliminate PVCs in these patients and markedly improve the quality of life of them.