摘要目的 探讨甲基苯丙胺(MA)依赖者抑郁症状与执行功能的相关性.方法 对强制隔离戒毒所内的165例MA依赖者进行一般资料问卷、Stroop色词测试(SCWT)、贝克抑郁自评量表(Beck depres-sion inventory,BDI)及贝克焦虑自评量表(Beck anxiety inventory,BAI)测试,对调查结果使用SPSS 17.0统计软件进行统计分析.结果 (1)单因素相关分析结果显示,抑郁严重程度分别与卡片A耗时数(r=0.251,P＜0.01)、卡片C耗时数(r=0.227,P＜0.01)呈正相关,而与卡片B耗时数(r=0.037,P＞0.05)、Stroop干扰效应(SIE)(r=0.075,P＞0.05)无相关;(2)多元线性逐步回归分析结果显示,在校正了性别、年龄、受教育年限等变量后,抑郁严重程度分别与卡片A耗时数(β=2.454,P=0.003)、卡片C耗时数(β=5.509,P＜0.01)仍存在相关性.结论 MA急性戒断期伴有抑郁症状者的执行功能受损.

abstractsObjective To explore the correlation between depressive symptom and executive function in methamphetamine-dependent patients.Methods 165 methamphetamine-dependent patients were examined by a general information questionnaire,Stroop color-word test (SCWT),Beck depression inventory (BDI) and Beck anxiety inventory(BAI).SPSS 17.0 statistical software was used to analyze the survey results.Results There was a significant positive correlation between depressive symptom and the reaction time of completing cards A and C(r=0.251,P＜0.01.r=0.227,P＜0.01).However,there was no significant correlation between depressive symptom and the reaction time of completing cards B and the Stroop interference effects(r=0.037,P＞0.05.r=0.075,P＞0.05).Multivariate linear regression demonstrated that depressive symptom was associated with the reaction time of completing cards A and C (β=2.454,P=0.003.β=5.509,P＜0.01).Conclusion Executive function exists impairement in methamphetamine-dependent patients with depressive symptom.