摘要目的：观察天麻三七汤对高血压伴焦虑患者血压变异性的影响。方法64例高血压伴焦虑患者随机分为对照组（ n＝32）和治疗组（ n＝32），对照组给予西药降压药常规治疗，治疗组加用天麻三七汤治疗，两组均连续治疗8周，比较治疗前后两组患者24h动态血压、自评焦虑量表（ the self?rating anxiety scale，SAS）评分的变化，分析天麻三七汤的作用。结果（1）治疗后对照组和治疗组24 h平均收缩压（24 hSBP）[（130．13±3．81）mmHg，（123．56±4．37） mmHg]（1 mmHg＝0．133 kPa）均低于治疗前[（145．36±7．17） mmHg，（145．16±6．77） mmHg]，差异有统计学意义（ P＜0．01）；（2）治疗后对照组和治疗组24h收缩压变异、日间收缩压变异、夜间收缩压变异[（12．19±3．21） mmHg，（11．16±2．26） mmHg，（10．49±3．76） mmHg和（10．95±2．35） mmHg，（10．08±2．67） mmHg，（10．12±3．78）mmHg]均小于治疗前[（14．53±3．65） mmHg，（13．81±4．04） mmHg，（12．47±4．23） mmHg 和（16．73±7．90）mmHg，（16．06±4．14）mmHg，（13．65±4．92）mmHg]，差异有统计学意义（P＜0．01或P＜0．05）；治疗后两组间比较：治疗组在24 h收缩压变异、日间收缩压变异[（10．95±2．35） mmHg，（10．08±2．67）]小于对照组[（12．19±3．21） mmHg，（11．16±2．26） mmHg]差异有统计学意义（P＜0．01）；（3）治疗组治疗后SAS评分（36．68±3．88）低于治疗前（58．66±3．13），差异有统计学意义（P＜0．01）；组间比较：治疗组治疗后SAS评分（36．68±3．88）低于对照组（51．86＋2．62），差异有统计学意义（P＜0．01）。结论天麻三七汤联合西药治疗高血压伴焦虑患者可显著减小其血压变异性，并能改善焦虑症状。

abstractsObjective To observe the efficacy of modified Tianma?Sanqi Decoction on hypertension patients with anxiety. Methods Totally 64 hypertension patients with anxiety patients were randomly divid?ed into control group (32 cases) and treatment group (32 cases).The control group with standard medica?tions for hypertension and treatment group with addition of Tianma?Sanqi Decoction, and both groups were continuously treated for 8 weeks. The changes of 24 hours ambulatory blood pressure and SAS scores were compared.Results ( 1) After treatment in the control group and treatment group of 24 h mean systolic blood pressure (24 hSBP) ((130.13±3.81)mmHg,(123.56±4.37)mmHg) (1 mmHg=0.133 kPa) were lower than before treatment((145.36±7.17) mmHg,(145.16±6.77) mmHg) and the difference was statisti?cally significant( P<0.01).(2) After treatment in the control group and treatment group 24 h systolic pres?sure standard deviation,diurnal systolic pressure standard deviation and nocturnal systolic pressure standard deviation((12.19±3.21) mmHg,(11.16±2.26) mmHg,(10.49±3.76) mmHg and (10.95±2.35) mmHg, (10.08±2.67) mmHg,(10.12±3.78)mmHg) were lower than before treatment ((14.53±3.65) mmHg, (13.81±4.04) mmHg,(12.47±4.23) mmHg and (16.73±7.90)mmHg,(16.06±4.14)mmHg,(13.65± 4.92)mmHg),and the difference was statistically significant( P<0.01 or P<0.05).After treatment in the&nbsp;treatment group, 24 h systolic pressure standard deviation, nocturnal systolic pressure standard deviation ((10.95±2.35) mmHg,(10.08±2.67) mmHg) were lower than control group((12.19±3.21) mmHg, (11.16±2.26) mmHg) and the difference was statistically significant.( P<0.01).(3) After treatment in the treatment group,SAS scores (36.68±3.88) points were lower than before treatment (58.66±3.13) points and the difference was statistically significant(P<0.01).After treatment the SAS score ((36.68±3.88) points) in the treatment group was lower than control group((51.86+2.62) points).Conclusion The hypertension patients with anxiety treated with Tianma?Sanqi Decoction and benazapril can improve blood pressure variability and the symp?toms of anxiety.