摘要目的 探讨团体认知行为治疗对抑郁症患者的抑郁症状与社会功能的疗效.方法 将160例抑郁症患者随机分为干预组与对照组.干预组采用抗抑郁药物治疗合并团体认知行为治疗,对照组采用单一抗抑郁药物治疗.于治疗前、治疗8周后分别采用汉密尔顿抑郁量表(HAMD)及住院精神病人社会功能评定量表(SSFPI)对2组患者进行评分.结果 治疗8周后,干预组HAMD总分[(14.76±9.48)分]低于治疗前[(37.91± 10.58)分],SSFPI总分[(30.09±4.34)分]高于治疗前[(12.40±2.56)分],差异具有统计学意义(P＜0.01);治疗8周后,干预组HAMD总分低于对照组[(20.71±7.85)分],SSFPI总分高于对照组[(22.63±3.63)分],差异具有统计学意义(P＜0.01).结论 在单用抗抑郁药物治疗的基础上合并团体认知行为治疗,可更为有效的改善抑郁症患者的抑郁症状和社会功能.

abstractsObjective To explore the efficacy of group cognitive behavioral therapy for improving depressive symptoms and social functional in patients with major depressive disorder.Methods A total of 160 patients with major depressive disorder were randomly divided into intervention group (n=80) and control group (n=80).Intervention group was treated with conventional antidepressants combined with group cognitive behavioral therapy.Control group was treated with one conventional antidepressants.All participants were assessed with Hamilton Depression Scale (HAMD)and Scale of Social function of Psychosis Inpatients (SSFPI) before and 8 weeks after the treatment.Results After 8 weeks treatment,the scores of HAMD (14.76±9.48) was significantly reduced and the scores of SSFPI(30.09±4.34) were significantly increased in intervention group compared with the baseline ((37.91± 10.58),(12.40±2.56),all P＜0.01).The scores of HAMD were significantly lower and the scores of SSFPI were significantly higher in intervention group than that in control group((20.71±7.85),(22.63±3.63),all P＜0.01).Conclusion Group cognitive behavioral therapy is effective for major depressive disorder patients by reducing depressive symptom and improving social function.