摘要目的 探讨中晚期非小细胞肺癌患者抑郁情绪现状及特点,分析心理弹性在自我感受负担与抑郁情绪间的中介作用.方法 采用简单随机抽样法抽取湖南省长沙市5所三级医院的306名新确诊中晚期非小细胞肺癌患者,在其出院前采用一般情况调查表,Zung抑郁自评量表,肺癌患者自我感受负担量表和心理弹性量表进行调查.采用 Pearson分析法分析三者间的相关关系,采用Amos7. 0建立结构方程模型并进行中介效应检验.结果 (1)新确诊中晚期非小细胞肺癌患者抑郁情绪总分为(59. 10± 8. 37)分,心理弹性总分为( 52. 77± 10. 12)分,自我感受负担总分为( 49. 64± 8. 55)分. (2)Pearson分析结果显示:抑郁总分与心理弹性总分及乐观、自强、坚韧三维度间均呈显著负相关(P<0. 05),与自我感受负担总分及身体,情感,疾病症状,社会与经济四维度间呈显著正相关(P<0. 05). (3)结构方程模型结果显示,心理弹性在自我感受负担与抑郁间起部分中介作用,中介效应占总效应的29. 8%.结论 新确诊中晚期非小细胞肺癌患者的抑郁情绪处于轻中度水平,可通过改善患者因肺癌而产生的自我感受负担,提高肺癌患者的心理弹性,从而缓解其抑郁情绪.

abstractsObjective To explore the present situation and characteristics of depression in patients with non-small cell lung cancer (NSCLC),and to analyze the mediating role of resilience in the relationship between self-perceived burden and depressive symptom,so as to provide evidence for improving depression in patients. Methods A total of 306 subjects from 5 tertiary hospitals in Changsha,Hunan Province were se-lected by simple random sampling method. Before their discharge from hospital,those subjects were investiga-ted by self-made social demographic questionnaire,Self-rating Depression Scale(SDS),Self-perceived Bur-den Scale of Lung Cancer(SPBS-LC) and Connor&Davidson Resilience Scale(CD-RISC). Pearson analysis was used to analyze the correlation among the variables,and Amos 7. 0 was used to establish the structural e-quation model and test the mediating effect. Results ( 1) The total score of depression was ( 59. 10 ± 8. 37). The total scores of resilience and self-perception burden were (52. 77±10. 12) and (49. 64±8. 55) in newly-diagnosed advanced non-small cell lung cancer patients. (2) Pearson analysis showed that the total score of depression was negatively correlated with the total score of resilience,optimism,self-improvement and tenacity (P<0. 05). The total score of depression was positively correlated with the total score of self-percep-tion burden, physical burden, emotional burden, disease symptoms, social and economic dimensions (P<0. 05). (3) Structural equation model analysis showed that resilience played a partial role in mediating be-tween self-perceived burden and depression and mediating effect accounted for 29. 8% of the total effect. Conclusion The depressive symptom of the NSCLC patients is at the mild to moderate level. Reducing their self-perceived burden and promoting the resilience of lung cancer patients could alleviate their depressive symptom.