摘要双重任务行走(dual task walking,DTW)是指在自然行走的同时执行另一项注意力需求的任务.在日常生活中很常见,如行走时的交谈,或者穿过大街的同时接打电话等.正常情况下,人们能够同时完成日常生活中的双重任务行走,但当本身步态受损或存在认知功能障碍时,双重任务的表现就会下降.神经退行性疾病(neurodegenerative disease,NDD)主要表现为运动及认知功能障碍,严重影响患者的日常生活活动能力.近年来,有关NDD患者DTW的研究发现,DTW的表现下降可能是NDD患者的特征,这可能对早期识别NDD,并预测疾病的进展具有重要的临床价值,且未来可能通过有效的DTW训练改善患者的日常生活活动能力,对NDD患者的康复很重要.本文主要综述了DTW的定义、常用方法、机制,以及DTW在NDD患者中的临床研究结果和应用,为进一步的临床研究提供理论依据.

abstractsDual task walking ( DTW) refers to the task of performing another attentional demand while walking naturally. It is quite common in our daily life,such as having a conversation while walking,or taking a call while crossing the street. People can simultaneously perform dual tasks normally. However,the performance of dual tasks will decline when the gait is impaired or cognitive dysfunction occurs. Neurodegen-erative disease (NDD) is mainly characterized by motor and cognitive dysfunction,which seriously affects patients' ability of daily living activities. In recent years,studies on DTW in patients with NDD have found that decreased performance of DTW may be a feature of NDD patients,which may have important clinical val-ue for early identification of NDD and predict disease progression. In the future,effective DTW training may improve the patients' ability of daily living activities,and it is important for the rehabilitation of NDD pa-tients. This article mainly reviews the definition,common methods and mechanisms of DTW,as well as the clinical research findings and applications of DTW in patients with NDD,and provides theoretical basis for further clinical research.