摘要目的:探讨强迫症患者的童年创伤与强迫症状、内隐外显记忆之间的相关性。方法:纳入52例强迫症患者，使用童年期创伤性经历问卷(childhood trauma questionnaire-short form，CTQ-SF)调查患者童年期创伤经历，耶鲁布朗强迫症状量表(Yale-Brown scale for obsessive-compulsive symptoms，Y-BOCS)评估患者强迫程度，词汇知觉速度测验任务及词汇识别任务测试被试的内隐记忆及外显记忆水平。根据CTQ-SF评分，将患者分为虐待组( n＝26)和忽视组( n＝26)，采用SPSS 22.0软件进行 t检验、Pearson相关性分析。 结果:虐待组与忽视组患者的强迫症状、内隐记忆、外显记忆的差异无统计学意义( t＝-1.959~1.839，均 P>0.05)。强迫思维得分[(12.52±4.61)分]与CTQ-SF总分[(40.10±10.20)分]呈正相关( r＝0.331， P<0.05)；分量表中，强迫思维得分与躯体虐待得分[(7.89±3.02)分]、性虐待得分[(6.47±2.28)分]呈正相关( r＝0.373， P<0.01； r＝0.356， P<0.05)。躯体虐待得分与外显记忆准确性[(68.75±13.33)%]呈负相关( r＝-0.281， P<0.05)；躯体忽视得分[(8.98±2.67)分]与内隐记忆反应时[(4 285.94±2 067.42)ms]呈正相关( r＝0.314， P<0.05)。 结论:强迫症患者的强迫思维与童年创伤经历，尤其与躯体虐待、性虐待相关。躯体创伤可能会影响患者的内隐、外显记忆水平。

abstractsObjective:To explore the correlation among childhood trauma, obsessive-compulsive symptoms, and implicit and explicit memory in patients with obsessive-compulsive disorder(OCD).Methods:Fifty-two OCD patients were enrolled, and the childhood trauma was investigated by using the childhood trauma questionnaire short-form(CTQ-SF). The degree of obsessive-compulsive symptoms was assessed by using the Yale-Brown obsessive symptoms scale (Y-BOCS). In addition, the abilities of implicit memory and explicit memory were tested by vocabulary perception speed tasks and vocabulary recognition tasks.According to the scores of CTQ-SF, the patients were divided into abuse group( n=26) and neglect group( n=26). SPSS 22.0 software was used for t-test and Pearson correlation analysis. Results:Results of obsessive-compulsive symptoms, implicit memory, and explicit memory showed no differences between the abuse group and the neglect group( t=-1.959-1.839, P>0.05). The scores of obsessions symptoms(12.52±4.61) were positively correlated with the total scores of CTQ-SF (40.10±10.20)( r=0.331, P<0.05). On the subscale, the scores of obsessions were positively correlated with the scores of physical abuse(7.89±3.02), sexual abuse(6.47±2.28)( r=0.373, P<0.01, r=0.356, P<0.05). There was a negative correlation between the scores of physical abuse and the accuracy of explicit memory(68.75±13.33)( r=-0.281, P<0.05). The scores of physical neglect(8.98±2.67) was positively correlated with implicit memory response time(4 285.94±2 067.42)( r=0.314, P<0.05). Conclusion:Obsessions in patients with OCD are related to traumatic childhood experiences, especially physical abuse and sexual abuse.Physical trauma may influence the level of implicit and explicit memory in patients with OCD.