摘要目的:探讨医务人员的压力知觉对抑郁情绪的影响，以及心理弹性在其中发挥的作用。方法:2020年2—3月，通过网络发布方式招募606名医务工作者，采用自行设计调查问卷、压力知觉量表(perceived stress scale，PSS-10)、心理弹性量表简化版(10-item Connor-Davidson resilience scale，CD-RISC-10)和健康问卷抑郁自评量表(patient health questionnaire-9，PHQ-9)进行调查。基于SPSS 26.0软件进行Pearson或Spearman相关分析、共同方法偏差检验、多重共线性检验；采用PROCESS 3.2程序中Model 4以及Bootstrap法进行中介效应分析。结果:606名医务人员的压力知觉评分[(16.93±6.65)分]与抑郁情绪评分[5.00(2.00，9.00)分]呈正相关( r＝0.551， P<0.01)，与心理弹性评分[(27.08±8.68)分]呈负相关( r＝－0.285， P<0.01)；医务人员心理弹性评分与抑郁情绪评分呈负相关( r＝－0.474， P<0.01)。中介效应分析表明，在压力知觉与抑郁情绪的关系中，心理弹性发挥了部分中介的作用，中介效应占总效应的10.87%。 结论:压力知觉可以直接或间接地对抑郁情绪产生影响，而且心理弹性在压力知觉和抑郁情绪间存在部分中介作用，临床上可以通过降低医务人员的压力知觉或提升其心理弹性来减少抑郁情绪的产生。

abstractsObjective:To explore the impact of stress perception on depression and the potential mediating role of resilience in medical staff.Methods:A total of 606 medical staff were recruited and investigated by self-designed questionnaire, the perceived stress scale (PSS-10), the 10-item Connor-Davidson resilience scale (CD-RISC-10), and the patient health questionnaire-9 (PHQ-9) from February to March, 2020.SPSS 26.0 software was used to execute Pearson or Spearman correlation analysis, common method biases test, and multicollinearity test.Model 4 in PROCESS 3.2 macro program and Bootstrap method were used for mediating effects analysis.Results:There was a positive correlation between stress perception score(16.93±6.65) and depression score (5.00(2.00, 9.00))( r=0.551, P<0.01), and a negative correlation between stress perception score and resilience score (27.08±8.68) ( r=-0.285, P<0.01) among 606 medical staff.There was a negative correlation between resilience score and depression score ( r=-0.474, P<0.01). Mesometric effect examination showed that resilience played a partial mediating role in the relationship between stress perception and depression, and the mediating effect accounted for 10.87% of the total effect. Conclusion:Stress perception can directly or indirectly influence depression scores, and resilience partially mediates the relationship between stress perception and depression.Depression can be reduced clinically by reducing stress perception or enhancing the resilience of medical personnel.