摘要目的:探讨孤独症谱系障碍(ASD)儿童感觉信息处理及自我调节能力与临床症状的相关性。方法:于2023年12月1日至2024年5月1日纳入符合标准的3～7岁ASD儿童73例，按临床症状分为轻度组( n＝20)、中度组( n＝26)、重度组( n＝27)。采用感觉讯息处理及自我调节功能量表(SPSRC)评估感觉信息处理及自我调节功能。采用社交反应量表(SRS)、孤独症行为量表(ABC)、儿童孤独症评定量表(CARS)评估ASD临床症状。使用SPSS 25.0并采用卡方检验、单因素方差分析、Pearson相关性分析进行统计学分析。 结果:ASD儿童感觉信息处理的6个版块(听觉、视觉、触觉、味嗅觉、前庭平衡觉及本体觉)异常率分别为31.51%(23/73)、32.88%(24/73)、32.88%(24/73)、32.88%(24/73)、24.66%(18/73)、27.40%(20/73)，自我调节能力3个版块(生理状况、情绪调节及适应能力)异常率分别为38.36%(28/73)、49.32%(36/73)、31.51%(23/73)。重度组SPSRC各版块异常率高于中度组和轻度组(均 P<0.05)。SPSRC各版块总得分与SRS、ABC及CARS总分均呈负相关( r＝－0.648～－0.236，均 P<0.05)。 结论:ASD儿童感觉信息处理及自我调节能力损害越明显其临床症状越重，感觉信息处理及自我调节能力的改善可能有助于ASD儿童康复治疗。

abstractsObjective:To explore the correlation among sensory information processing, self-regulation abilities, and clinical symptoms in children with autism spectrum disorder (ASD).Methods:From December 1, 2023 to May 1, 2024, a total of 73 ASD children aged 3-7 years old meeting the inclusion criteria were recruited, and they were divided into mild group ( n=20), moderate group ( n=26), and severe group ( n=27) based on clinical symptoms.The sensory processing and self-regulation checklist (SPSRC) was used to assess sensory processing and self-regulation abilities. Clinical symptoms of ASD were assessed by the social responsiveness scale (SRS), the autism behavior checklist (ABC), and the childhood autism rating scale (CARS). Statistical analysis was conducted by SPSS 25.0 software, including Chi-square test, one-way ANOVA, and Pearson correlation analysis. Results:Abnormal rates of sensory processing across the six domains in ASD children were as follows: auditory (31.51%, 23/73), visual (32.88%, 24/73), tactile (32.88%, 24/73), gustatory/olfactory (32.88%, 24/73), vestibular (24.66%, 18/73), and proprioception (27.40%, 20/73).Abnormal rates of self-regulation abilities across the three domains were as follows: physiological state (38.36%, 28/73), emotional regulation (49.32%, 36/73), and adaptability (31.51%, 23/73).The severe group showed higher abnormal rates in SPSRC domains compared to the moderate and mild groups (all P<0.05). Total scores of each SPSRC domain were negatively correlated with total scores of SRS, ABC, and CARS ( r=-0.648--0.236, all P<0.05). Conclusion:The more severe the impairment in sensory processing and self-regulation abilities in ASD children, the more severe their clinical symptoms. Improving sensory processing and self-regulation abilities may contribute to the rehabilitation of children with ASD.