The PI3K/mTOR dual inhibitor BEZ235 suppresses proliferation and migration and reverses multidrug resistance in acute myeloid leukemia

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作者单位 Department of Hematology/Key Laboratory of Malignant Tumor Gene Regulation and Target Therapy of Guangdong Higher Education Institutes, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China;Department of Hematology, Zhujiang Hospital, Southern Medical University, Guangzhou 501282, China ^[1] Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China ^[2] Department of Hematology/Key Laboratory of Malignant Tumor Gene Regulation and Target Therapy of Guangdong Higher Education Institutes, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China ^[3] Biophysics Department of Oregon State University, ALS-2139 Corvallis, OR 97330, USA ^[4] Department of Hematology, Zhujiang Hospital, Southern Medical University, Guangzhou 501282, China ^[5]

关键词 acute myeloid leukemia HL-60/VCR cells K562/ADR cells chemoresistance PI3K/mTOR BEZ235 miR-1-3p BAG4 EDN1 ABCB1

栏目名称 Chemotherapy and Antimicrobial

DOI 10.1038/aps.2016.121

发布时间 2017-03-31

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中国药理学报（英文版）

2017年38卷3期

382-391页

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The PI3K/mTOR dual inhibitor BEZ235 suppresses proliferation and migration and reverses multidrug resistance in acute myeloid leukemia

中国药理学报（英文版）

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中国药理学报（英文版）

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The PI3K/mTOR dual inhibitor BEZ235 suppresses proliferation and migration and reverses multidrug resistance in acute myeloid leukemia

中国药理学报（英文版）

相似文献

中国药理学报（英文版）

相关期刊

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