LW-213 induces cell apoptosis in human cutaneous T-cell lymphomas by activating PERK-eIF2α-ATF4-CHOP axis

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作者 Xiao-xuan Yu ^[1] Meng-yuan Zhu ^[2] Jia-rong Wang ^[2] Hui Li ^[2] Po Hu ^[2] Ying-jie Qing ^[2] Xiang-yuan Wang ^[2] Hong-zheng Wang ^[2] Zhan-yu Wang ^[2] Jing-yan Xu ^[3] Qing-long Guo ^[2] Hui Hui ^[2] 学术成果认领

作者单位 State Key Laboratory of Natural Medicines,Jiangsu Key Laboratory of Carcinogenesis and Intervention,Key Laboratory of Drug Quality Control and Pharmacovigilance,Ministry of Education,Jiangsu Key Laboratory of Drug Design and Optimization,China Pharmaceutical University,Nanjing 211198,China;Department of Pharmacology,School of Medicine&Holostic Integrative Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China ^[1] State Key Laboratory of Natural Medicines,Jiangsu Key Laboratory of Carcinogenesis and Intervention,Key Laboratory of Drug Quality Control and Pharmacovigilance,Ministry of Education,Jiangsu Key Laboratory of Drug Design and Optimization,China Pharmaceutical University,Nanjing 211198,China ^[2] Department of Hematology,The Affiliated Drum Tower Hospital of Nanjing University Medical School,Nanjing 210000,China ^[3]

关键词 CTCL LW-213 wogonin flavonoids ER stress ROS calcium apoptosis NAC 2-APB

栏目名称 Chemotherapy

DOI 10.1038/s41401-020-0466-7

发布时间 2021-03-12

基金项目

This work was supported by the National Natural Science Foundation of China the Drug Innovation Major Project Natural Science Foundation of Jiangsu Province Nanjing Medical Science and Technology Development Project Research and Innovation Project for College Graduates of Jiangsu Province China Postdoctoral Science Foundation and"Double First-Class"University project

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中国药理学报（英文版）

2021年42卷2期

290-300页

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LW-213 induces cell apoptosis in human cutaneous T-cell lymphomas by activating PERK-eIF2α-ATF4-CHOP axis

中国药理学报（英文版）

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中国药理学报（英文版）

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LW-213 induces cell apoptosis in human cutaneous T-cell lymphomas by activating PERK-eIF2α-ATF4-CHOP axis

中国药理学报（英文版）

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中国药理学报（英文版）

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